Results 191 to 200 of about 8,851,390 (349)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Measuring individual differences in the speed of attention using the distractor intrusion task. [PDF]

Behav Res Methods
Zivony A, von Bastian CC, Pye R.
europepmc   +1 more source

Individual differences in cognitive control modulate cognitive biases linked to depressive symptoms [PDF]

, 2016
Everaert, Jonas, Grahek, Ivan, Koster, Ernst   +2 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Individual differences in feelings of certainty surrounding mixed emotions. [PDF]

PLoS One
Vaccaro AG, Shakthivel S, Wu H, Iyer R, Kaplan J.   +4 more
europepmc   +1 more source

Individual differences in working memory predict the efficacy of experimenter-manipulated gestures in first-grade children [PDF]

Eliza L. Congdon
openalex   +1 more source

Individual differences in endogenous opioid function predict analgesic responses to morphine [PDF]

, 2013
Stephen Bruehl, John W. Burns, Rajnish K. Gupta, Asokumar Buvanendran, Steven D. Passik, Christopher France, Melissa Chont, Ellen Kinner, Erik Schuster, L. Vilardo   +9 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Mapping individual differences in intermodal coupling in neurodevelopment. [PDF]

Imaging Neurosci (Camb)
Pan R, Weinstein SM, Tu D, Hu F, Tanrıverdi B, Zhang R, Vandekar SN, Baller EB, Gur RC, Gur RE, Alexander-Bloch AF, Satterthwaite TD, Park JY.   +12 more
europepmc   +1 more source

7756 Gonadectomy in Individuals with Differences of Sex Development - A Prospective I-DSD Registry Study [PDF]

Michele Ann O'Connell, Angela Lucas-Herald, Jillian Bryce, Minglu Chen, Justin H. Davies, Margarett Shnorhavorian, Navoda Atapattu, Inna Bachynska, Niels Birkebæk, Martine Cools, Korcan Demir, Liat de Vries, Heba Elsedfy, Mohamed Abdelsabour Fahmy, Evgenia Globa, Romina P. Grinspon, Guilherme Guaragna‐Filho, Gil Guerra‐Júnior, Dominika Januś, Zofia Kolesińska, Inas Mazen, Susan O’Çonnell, Sumudu Nimali Seneviratne, Marianna Rita Stancampiano, Gilvydas Verkauskas, S. Faisal Ahmed   +25 more
openalex   +1 more source