Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Cognitive Individual Differences in Multilingualism: Language Aptitude and Working Memory in L3 Learners. [PDF]
Öztekin E, Erçetin G.
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Individual differences in motives for costly punishment. [PDF]
Claessens S, Atkinson QD, Raihani NJ.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Individual Differences in Detecting and Correcting Logical Errors in Mathematical Texts. [PDF]
Luo Z, Yang X, Zhang Y, Xiong B.
europepmc +1 more source
Individual differences in speech monitoring: Functional and structural correlates of delayed auditory feedback. [PDF]
Ozker M +4 more
europepmc +1 more source
From early to contemporary normative modeling: Mapping individual differences in neurophysiological signals. [PDF]
Mallus FA +7 more
europepmc +1 more source
Parallel activation of multiple languages in trilinguals: Evidence from eye movements and individual differences. [PDF]
Fridman C, Meir N, Marian V.
europepmc +1 more source

