Results 81 to 90 of about 8,926,613 (305)

Different tastes for different individuals [PDF]

open access: yes, 2014
Abstract Individual taste differences were first reported in the first half of the 20th century, but the primary reasons for these differences have remained uncertain. Much of the taste variation among different mammalian species can be explained by pseudogenization of taste receptors.
openaire   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

The dynamical signature of anhedonia in major depressive disorder: positive emotion dynamics, reactivity, and recovery

open access: yesBMC Psychiatry, 2019
Background Major Depressive Disorder (MDD) is the leading cause of disability worldwide. The cardinal features of MDD are depressed mood and anhedonia. Anhedonia is defined as a “markedly diminished interest or pleasure in all, or almost all, activities ...
Vera E. Heininga   +7 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Preprocessing Experience-Sampling-Method Data: A Step-by-Step Framework, Tutorial Website, R Package, and Reporting Templates

open access: yesAdvances in Methods and Practices in Psychological Science
Experience-sampling-method (ESM) studies have become a very popular tool to gain insight into the dynamics of psychological processes. Although the statistical modeling of ESM data has been widely studied, the preprocessing steps that precede such ...
Jordan Revol   +5 more
doaj   +1 more source

Learning is enhanced by tailoring instruction to individual genetic differences. [PDF]

open access: yes, 2019
It is widely argued that personalized instruction based on individual differences in learning styles or genetic predispositions could improve learning outcomes.
Brainard, Michael S, Mets, David G
core  

Feature-Based Change Detection Reveals Inconsistent Individual Differences in Visual Working Memory Capacity [PDF]

open access: yes, 2016
Visual working memory (VWM) is a key cognitive system that enables people to hold visual information in mind after a stimulus has been removed and compare past and present to detect changes that have occurred. VWM is severely capacity limited to around 3–
Aaron T. Buss   +29 more
core   +3 more sources

Individuality as Difference

open access: yesPhilosophy & Public Affairs
Today’s culture tells us to respect, even celebrate, the many ways in which we are different from each other. These are moral claims about how to relate to people, given that they are different. But does it also matter whether we are different in the first place?
openaire   +3 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Attachment preference in auditory German sentences: Individual differences and pragmatic strategy

open access: yes, 2019
Relative clauses modify a preceding element, but as this element can be flexibly located, the point of attachment is sometimes ambiguous. Preference for this attachment can vary within languages such as German, yet explanations for differences in ...
Harding, E., Kotz, S., Sammler, D.
core   +1 more source

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