Results 151 to 160 of about 3,634,171 (267)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Etiological Insights and the Role of Individual Factors in Infectious Spondylodiscitis. [PDF]

Infect Dis Rep
Vulpe DE, Nedelea DG, Dragosloveanu S, Sandulescu O, Scheau C.   +4 more
europepmc   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Risk Factors Associated With Osteochondral Fractures After Lateral Patellar Dislocation Based on Individual Factors. [PDF]

Orthop J Sports Med
Li K, Xu C, Li C, Cui X, Ni Z, Ji W, Wang F.   +6 more
europepmc   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Association between care complexity individual factors and older inpatients with COVID-19: a cross-sectional study. [PDF]

Front Aging
Adamuz J, González-Vaca J, González-Samartino M, López-Jiménez MM, Urbina A, Polushkina-Merchanskaya O, Alonso-Fernández S, Esteban-Sepúlveda S, Barrientos-Trigo S, Juvé-Udina ME.   +9 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Impact of Individual Factors on Careless Responding Across Different Mental Disorder Screenings: Cross-Sectional Study. [PDF]

J Med Internet Res
Kuang H, Zhu L, Yin H, Zhang Z, Jing B, Kuang J.   +5 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Individual Factors That Affect Laypeople's Understanding of Definitions of Medical Jargon. [PDF]

Health Policy Technol
Levy DA, Jordan HS, Lalor JP, Smirnova JK, Hu W, Liu W, Yu H.   +6 more
europepmc   +1 more source