Results 121 to 130 of about 8,564,030 (285)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

THE IDENTIFICATION OF THE INDIVIDUAL [PDF]

open access: yesAmerican Anthropologist, 1896
openaire   +1 more source

The value of individual identification in studies of free-living hyenas and aardwolves. [PDF]

open access: yesMamm Biol, 2022
Spagnuolo OSB   +3 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Identification of Nonlinear Time Lag Systems by Improved Genetic Algorithm [PDF]

open access: yes, 1999
In this paper. a new identification method is proposed which can obtain a good accuracy of identification of nonlinear time lag system on the basis of combination of genetic algorithm and sequence method.
ASAKURA, Toshiyuki, GUO, Qingzhi
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Precision Identification from a Multi-omics Perspective: Current Status, Challenges, and Prospects in Forensic Genetics ZHU Bo-feng

open access: yesFayixue Zazhi
Driven by the deep integration and continuous advancement of multi-omics technologies, forensic genetics has been rapidly transforming from traditional marker-based detection to more refined and intelligent approaches in recent years.
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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