Results 151 to 160 of about 8,564,030 (285)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Recursive partitioning based approaches for low back pain subgroup identification in individual patient data meta-analyses [PDF]

open access: yes
This thesis presents two novel approaches for performing subgroup analyses or identifying subgroups in an individual patient data (IPD) meta-analyses setting. The work contained in this thesis originated from an important research priority in the area of
Mistry, Dipesh
core  

CzechLynx: A Dataset for Individual Identification and Pose Estimation of the Eurasian Lynx. [PDF]

open access: yesSci Data
Picek L   +16 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Evaluation of 5-Methylthioninhydrin for the Detection of Fingermarks on Porous Surfaces and Comparison

open access: yes, 2006
The chemical 5-methylthioninhydrin was developed in the early 1990s for treating fingermarks on porous surfaces. Although many researchers showed the promise of this chemical during the years between 1990 and 1997, current research indicates that this ...
Wallace   +4 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Placing anurans in water can improve photo-based individual identification. [PDF]

open access: yesPLoS One
Nemesházi E   +5 more
europepmc   +1 more source

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