Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Recursive partitioning based approaches for low back pain subgroup identification in individual patient data meta-analyses [PDF]
This thesis presents two novel approaches for performing subgroup analyses or identifying subgroups in an individual patient data (IPD) meta-analyses setting. The work contained in this thesis originated from an important research priority in the area of
Mistry, Dipesh
core
CzechLynx: A Dataset for Individual Identification and Pose Estimation of the Eurasian Lynx. [PDF]
Picek L +16 more
europepmc +1 more source
Verification of Natural Marking for Individual Identification Using a Duplex Marking Approach in Ijima's Sea Snakes, Emydocephalus ijimae (Reptilia: Elapidae). [PDF]
Yamamoto T, Nakamura T, Toda M.
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The chemical 5-methylthioninhydrin was developed in the early 1990s for treating fingermarks on porous surfaces. Although many researchers showed the promise of this chemical during the years between 1990 and 1997, current research indicates that this ...
Wallace +4 more
core
Detection, communication, and individual identification with deep audio embeddings: A case study with North Atlantic right whales. [PDF]
Tolkova I +4 more
europepmc +1 more source
The Time-Robustness Analysis of Individual Identification Based on Resting-State EEG. [PDF]
Di Y, An X, Zhong W, Liu S, Ming D.
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Placing anurans in water can improve photo-based individual identification. [PDF]
Nemesházi E +5 more
europepmc +1 more source

