Results 91 to 100 of about 2,368,157 (325)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012 A new scheduling method is proposed, in this paper, to consider the statistical distributions of the processing times which are represented by normal distributions for the manufacturing systems where the human operators carry out the machining operations
Koji IWAMURA +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Remote SensingEstimating individual tree Above-Ground Biomass (AGB) is essential for assessing ecological functions and carbon storage in both forest and urban environments.
Sina Jarahizadeh, Bahram Salehi
doaj +1 more source
Meniscus injury prediction model based on metric learning [PDF]
PeerJ Computer ScienceA meniscus injury is a prevalent condition affecting the knee joint. The construction of a subjective prediction model for meniscus injury represents a potentially invaluable diagnostic tool for physicians.
Yu Wang +7 more
doaj +2 more sources
Comparison of signalized junction control strategies using individual vehicle position data
, 2010 This paper is concerned with the development of control strategies for urban signalized junction that can make use of individual vehicle position data from localization probes on board the vehicles.
Box, S., Waterson, B.J.
core
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source