Results 101 to 110 of about 6,555,116 (242)

Neural machine translation of literary texts from English to Slovene

, 2019
Neural Machine Translation has shown promising performance in literary texts. Since literary machine translation has not yet been researched for the English-toSlovene translation direction, this paper aims to fulfill this gap by presenting a comparison ...
Kuzman, Taja, Arčan, Mihael, Vintar, Špela   +2 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

MATEO : MAchine Translation Evaluation Online

, 2023
We present MAchine Translation Evaluation Online (MATEO), a project that aims to facilitate machine translation (MT) evaluation by means of an easy-to-use web interface that can evaluate given machine translations with a battery of automatic metrics.
Vanroy, BramUGent0001615296528020026585439747705382060000-0002-4622-8364C50B0474-7EE0-11E7-B38D-2BA4AD28A064, Popovic, Majaeditor, Brenner, Juditheditor, Nurminen, Maryeditor, Mikhailov, Mikhaileditor, Forcada, Mikeleditor, Alvarez Vidal, Sergieditor, Scarton, Carolinaeditor, Ranasinghe, Tharindueditor, Koponen, Maariteditor, Aranberri, Noraeditor, Parra Escartín, Carlaeditor, Latomaa, Sirkkueditor, Nunziatini, Maraeditor, Tezcan, ArdaLW220020058519838020017673550000-0002-8707-6176E4E9C51C-9502-11E3-A4F6-4F4B11BDE39D, Macken, LieveLW228020002457680000-0001-7516-7487F93DB0F6-F0ED-11E1-A9DE-61C894A0A6B4, Vanmassenhove, Evaeditor, Schierl, Frederikeeditor, Moniz, Helenaeditor   +18 more
core  

Current Control in Field-Excited Flux Switching Machines: No-Load Induced Voltage Impact Based on the Winding Connection

Eletrônica de Potência
Micro and mild hybrid electric vehicles can make a significant contribution to reducing emissions and mitigating the environmental impact. Electric machine designs with fewer or no rare-earth permanent magnets will play an important role in the adoption
Diogo P. V. Galo, Thales A. C. Maia, Braz de J. Cardoso Filho   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Personalized assessment and training of neurosurgical skills in virtual reality: An interpretable machine learning approach

Virtual Reality & Intelligent Hardware
Background: Virtual reality technology has been widely used in surgical simulators, providing new opportunities for assessing and training surgical skills.
Fei Li, Zhibao Qin, Kai Qian, Shaojun Liang, Chengli Li, Yonghang Tai   +5 more
doaj   +1 more source