Results 61 to 70 of about 2,229,955 (197)

Predictors of seizure outcomes in children with tuberous sclerosis complex and intractable epilepsy undergoing resective epilepsy surgery: an individual participant data meta-analysis. [PDF]

, 2013
ObjectiveTo perform a systematic review and individual participant data meta-analysis to identify preoperative factors associated with a good seizure outcome in children with Tuberous Sclerosis Complex undergoing resective epilepsy surgery.Data ...
Banfield, Laura, Bhandari, Mohit, Bhatnagar, Neera, Ebrahim, Shanil, Fallah, Aria, Guyatt, Gordon H, Ibrahim, George M, Kulkarni, Abhaya V, Liang, Shuli, Liao, Jianxiang, Mansouri, Alireza, Reddy, Deven, Rutka, James T, Snead, O Carter, Teutonico, Federica, Walter, Stephen D   +15 more
core   +2 more sources

Oxcarbazepine versus phenytoin monotherapy for epilepsy: an individual participant data review [PDF]

Cochrane Database of Systematic Reviews, 2018
This is an updated version of the Cochrane Review previously published in 2013. This review is one in a series of Cochrane Reviews investigating pair-wise monotherapy comparisons.Epilepsy is a common neurological condition in which abnormal electrical discharges from the brain cause recurrent unprovoked seizures. It is believed that with effective drug
Nevitt, SJ, Marson, AG, Tudur Smith, C
openaire   +4 more sources

Individual participant data systematic reviews with meta-analyses of psychotherapies for borderline personality disorder

BMJ Open, 2021
Introduction The heterogeneity in people with borderline personality disorder (BPD) and the range of specialised psychotherapies means that people with certain BPD characteristics might benefit more or less from different types of psychotherapy ...
Eirini Karyotaki, Pim Cuijpers, Erik Simonsen, Ole Jakob Storebø, Klaus Lieb, Jutta Stoffers-Winterling, Nicolas Derian, Anthony Bateman, Johanne Pereira Ribeiro, Mickey T Kongerslev, Mie Sedoc Jørgensen, Richard Kirubakaran   +11 more
doaj   +1 more source

Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ. [PDF]

, 2016
Meta-analysis using individual participant data (IPD) obtains and synthesises the raw, participant-level data from a set of relevant studies. The IPD approach is becoming an increasingly popular tool as an alternative to traditional aggregate data meta ...
Burke, DL, Ensor, J, Riley, RD
core   +2 more sources

Stakeholder perspectives on data sharing from pragmatic clinical trials: Unanticipated challenges for meeting emerging requirements

Learning Health Systems
Introduction Numerous arguments have been advanced for broadly sharing de‐identified, participant‐level clinical trial data. However, data sharing in pragmatic clinical trials (PCTs) presents ethical challenges.
Stephanie R. Morain, Juli Bollinger, Kevin Weinfurt, Jeremy Sugarman   +3 more
doaj   +1 more source

Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide

BMC Medical Research Methodology, 2020
Background Shifts in data sharing policy have increased researchers’ access to individual participant data (IPD) from clinical studies. Simultaneously the number of IPD meta-analyses (IPDMAs) is increasing.
Matthew Ventresca, Holger J. Schünemann, Fergus Macbeth, Mike Clarke, Lehana Thabane, Gareth Griffiths, Simon Noble, David Garcia, Maura Marcucci, Alfonso Iorio, Qi Zhou, Mark Crowther, Elie A. Akl, Gary H. Lyman, Viktoria Gloy, Marcello DiNisio, Matthias Briel   +16 more
doaj   +1 more source

Prediction of fruit and vegetable intake from biomarkers using individual participant data of diet-controlled intervention studies [PDF]

, 2015
Fruit and vegetable consumption produces changes in several biomarkers in blood. The present study aimed to examine the dose–response curve between fruit and vegetable consumption and carotenoid (α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein ...
Boshuizen, Hendriek C., Brazionis, Laima, Bub, Achim, Castenmiller, Jacqueline J. M., Chopra, Mridula, De Vries, Jeanne H. M., Dragsted, Lars O., Freese, Riitta, Itsiopoulos, Catherine, Karlsen, Anette, Miller, Edgar R., Naber, Ton H. J., O'Dea, Kerin, Pasman, Wilrike J., Souverein, Olga W., Van Der Voet, Hilko, Van Het Hof, Karin, Van Loo-Bouwman, Carolien A., Watzl, Bernhard, Winkels, Renate   +19 more
core   +1 more source

Investigating post-stroke fatigue: An individual participant data meta-analysis [PDF]

Journal of Psychosomatic Research, 2018
The prevalence of post-stroke fatigue differs widely across studies, and reasons for such divergence are unclear. We aimed to collate individual data on post-stroke fatigue from multiple studies to facilitate high-powered meta-analysis, thus increasing our understanding of this complex phenomenon.We conducted an Individual Participant Data (IPD) meta ...
Toby B. Cumming, Ai Beng Yeo, Jodie Marquez, Leonid Churilov, Jean-Marie Annoni, Umaru Badaru, Nastaran Ghotbi, Joe Harbison, Gert Kwakkel, Anners Lerdal, Roger Mills, Halvor Naess, Harald Nyland, Arlene Schmid, Wai Kwong Tang, Benjamin Tseng, Ingrid van de Port, Gillian Mead, Coralie English   +18 more
openaire   +4 more sources

Age differences between sexual partners, behavioural and demographic correlates, and HIV infection on Likoma Island, Malawi [PDF]

, 2016
Patterns of age differences between sexual partners-"age-mixing"-may partially explain the magnitude of HIV epidemics in Sub-Saharan Africa. However, evidence of age-disparity as a risk factor for HIV remains mixed.
Beauclair, Roxanne, Delva, Wim, Helleringer, Stéphane, Hens, Niel   +3 more
core   +2 more sources

Individual participant data meta-analyses compared with meta-analyses based on aggregate data [PDF]

Trials, 2011
Meta-analyses based on individual participant data (IPD-MAs) allow more powerful and uniformly consistent analyses as well as better characterisation of subgroups and outcomes, compared to those which are based on aggregate data (AD-MAs) extracted from published trial reports.
C. T. Smith, J. Oyee, M. Marcucci, M. Rovers, IORIO, Alfonso, R. Riley, P. Williamson, M. Clarke   +7 more
openaire   +4 more sources