Results 191 to 200 of about 43,105,901 (290)

Commentary: Like it and lump it? Meta-analysis using individual participant data [PDF]

International Journal of Epidemiology, 2010
openaire   +2 more sources

Metasurface‐Enabled Helical Wavefront Fingerprint Metrology for Quantitative Retrieval of Liquid Optical Constants

Advanced Science, EarlyView.
A metasurface‐enabled helical wavefront fingerprint (MHWF) paradigm is proposed for quantitative and specific retrieval of a liquid medium's refractive index and extinction coefficient. The liquid's complex dielectric response governs the wavefront evolution of the metasurface‐generated focused vortex beam, forming a distinctive three‐dimensional ...
Yuting Zhou, Hongliang Li, Simeng Li, Feiyu Jiao, Yansong Du, Jin Tae Kim, Sang‐Shin Lee, Duk‐Yong Choi, Fei Ding, Xuechao Yu, Xun Guan   +10 more
wiley   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Sex-based prognosis in industry-sponsored advanced solid tumor trials: an individual participant data meta-analysis of survival and adverse events. [PDF]

J Natl Cancer Inst
Chhetri R, Modi ND, Menz BD, Cornelisse E, Postma D, Kuderer NM, Lyman GH, Swain SM, Li LX, Abuhelwa AY, McKinnon RA, Vatandoust S, Kichenadasse G, Rowland A, Sorich MJ, Hopkins AM.   +15 more
europepmc   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

An individual participant data meta-analysis of how physical activity relates to affective well-being in daily life. [PDF]

Nat Hum Behav
Rehder J, Timm I, Berretz G, Reinhard I, Neubauer AB, Güntürkün O, Takano K, Bierbauer W, Cabrita M, Bourke M, Smyth J, Kim J, Michalak J, Curtiss J, Pannicke B, Gallagher JB, Abrantes AM, Nakamura T, Yamamoto Y, Cook P, Wieland LM, von Haaren-Mack B, McCormick B, Hachenberger J, Vetrovsky T, Henwood B, Poppe L, Sudeck G, Hollands L, Goldschmidt AB, Martire L, Kanning M, Maher JP, Li YM, Reininghaus U, Berli C, Seiferth C, Hevel DJ, Leger K, Staiano AE, Zeeck A, Calza S, Liao Y, Ruissen GR, CoCA Consortium, Schwerdtfeger AR, Haucke M, Pham LT, Liu S, Thomas MC, Meyer-Lindenberg A, Dunton GF, Elavsky S, Ebner-Priemer UW, Giurgiu M, Packheiser J, Reichert M.   +56 more
europepmc   +1 more source

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Intrauterine human chorionic gonadotropin administration before embryo transfer (IHABT): an individual participant data meta-analysis of randomized controlled trials. [PDF]

Hum Reprod Update
Zou H, Abdallah KS, Wirleitner B, Hong KH, Thanaboonyawat I, Laokirkkiat P, Hafezi M, Kokeguchi S, Makhlouf A, Libesman S, Nguyen D, Williams JG, Showell M, Gadalla M, Mol BWJ, Li W, Wang R.   +16 more
europepmc   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source