Results 31 to 40 of about 43,105,901 (290)

Individual participant data meta-analysis with mixed-effects transformation models [PDF]

open access: yesBiostatistics, 2021
SummaryOne-stage meta-analysis of individual participant data (IPD) poses several statistical and computational challenges. For time-to-event outcomes, the approach requires the estimation of complicated nonlinear mixed-effects models that are flexible enough to realistically capture the most important characteristics of the IPD.
Tamási, Bálint   +4 more
openaire   +2 more sources

Meta-analysis using individual participant data: one-stage and two-stage approaches, and why they may differ. [PDF]

open access: yes, 2016
Meta-analysis using individual participant data (IPD) obtains and synthesises the raw, participant-level data from a set of relevant studies. The IPD approach is becoming an increasingly popular tool as an alternative to traditional aggregate data meta ...

core   +1 more source

Meta-analysis of individual participant data: rationale, conduct, and reporting [PDF]

open access: yesBMJ, 2010
The use of individual participant data instead of aggregate data in meta-analyses has many potential advantages, both statistically and clinically. Richard D Riley and colleagues describe the rationale for an individual participant data meta-analysis and outline how to conduct this type of study Meta-analysis methods involve combining and analysing ...
Riley, RD, Lambert, PC, Abo-Zaid, G
openaire   +3 more sources

Dosage, intensity, and frequency of language therapy for Aphasia: A systematic review-based, individual participant data network meta-analysis [PDF]

open access: yes, 2021
Background and Purpose: Optimizing speech and language therapy (SLT) regimens for maximal aphasia recovery is a clinical research priority. We examined associations between SLT intensity (hours/week), dosage (total hours), frequency (days/week), duration
The REhabilitation and recovery of peopLE with Aphasia after StrokE (RELEASE) Collaborators   +1 more
core   +1 more source

Work stress and risk of cancer: meta-analysis of 5700 incident cancer events in 116 000 European men and women [PDF]

open access: yes, 2012
Objective To investigate whether work related stress, measured and defined as job strain, is associated with the overall risk of cancer and the risk of colorectal, lung, breast, or prostate cancers.Design Meta-analysis of pooled prospective individual ...
Burr, Herman,   +152 more
core   +1 more source

Commentary triggered by the Individual Participant Data Meta-Analysis Consortium study of job strain and myocardial infarction risk

open access: yesScandinavian Journal of Work, Environment & Health, 2014
Mika Kivimäki initiated the Individual Participant Data (IPD) Meta-Analysis Consortium, which currently has 50 members. The Consortium recently published several research reports on the relationship between job strain (high psychological demands and low ...
Töres Theorell
doaj   +1 more source

External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis

open access: yesBMC Medicine, 2020
Background Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management.
Kym I. E. Snell   +60 more
doaj   +1 more source

Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol

open access: yesSystematic Reviews, 2017
Background Preterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at birth and experience health problems during early childhood.
Lesley A. Stewart   +10 more
doaj   +1 more source

The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart

open access: yesMalaria Journal, 2022
Background The prevalence of small for gestational age (SGA) may vary depending on the chosen weight-for-gestational-age reference chart. An individual participant data meta-analysis was conducted to assess the implications of using a local reference ...
George Mtove   +20 more
doaj   +1 more source

Estimating interactions in individual participant data meta-analysis: a comparison of methods in practice

open access: yesSystematic Reviews, 2022
Medical interventions may be more effective in some types of individuals than others and identifying characteristics that modify the effectiveness of an intervention is a cornerstone of precision or stratified medicine.
Ruth Walker   +2 more
doaj   +1 more source

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