Results 81 to 90 of about 63,434 (255)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Tadeusz Klimski’s realistic interpretation of the problem of unity

open access: yes, 2013
Tadeusz Klimski devoted to the problem of unity dissertation, entitled “One and being. Analysis of the realistic concepts (Aristotle, St. Thomas Aquinas, modern Thomists)”, published in 1992.
Andrzejuk, Artur
core  

Science as a Self-Organizing Meta-Information System [PDF]

open access: yes, 2004
Four basic problems that a theory of science has to deal with concern epistemology, structure, causality, and dynamics of science. These problems deal with the relationship of induction/deduction, actors/structures, internal/external factors, and ...
Fuchs, Christian, Christian Fuchs
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Preserve the Unity of the Spirit

open access: yes, 1970
Surely there is no gift for the human race that we desire more at this hour than unity. Nations fight nations, classes stand embattled against classes, spouses and children draw apart from each other.
Caemmerer, Richard R., Sr.
core  

7. What is ultimately real—unity and activity

open access: yes, 2016
‘What is ultimately real—unity and activity’ uncovers Leibniz’s views about what is ultimately real in this actual world of which we have experience. What are the most fundamental, really existing things?
Maria Rosa Antognazza
core   +1 more source

A razão em Feuerbach como base da unidade do homem e da natureza [PDF]

open access: yesPrincípios, 2007
Feuerbach treats nature on his first work On the Infinitude, Unity, and Universality of Reason from the view point of pantheism which is seen by him as a source for superseding the dualism of spirit and nature, i.e., the reconciliation between the two ...
Eduardo Ferreira Chagas
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Deleuze's becoming-subject : difference and the human individual [PDF]

open access: yes
This study argues that a theory of the distinctively human Individual lies latent within Deleuze's readings of Hume and Bergson and his two major metaphysical treatises. This evolving theory derives from efforts to re-think the concept of 'the subject'
Stagoll, Clifford Scott
core  

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