Results 141 to 150 of about 3,332,191 (309)

Toward an ecological conception of timbre [PDF]

, 2002
This paper is part of a series in which we had worked in the last 6 months, and, specifically, intend to investigate the notion of timbre through the ecological perspective proposed by James Gibson in his Theory of Direct Perception.
Oliveira, André L. G., Oliveira, Luis F.   +1 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

DESAIN KURIKULUM YANG FLEKSIBEL UNTUK ANAK BERKEBUTUHAN KHUSUS PADA TK PANGUDI LUHUR VINCENTIUS

Jurnal Visi Ilmu Pendidikan
This research aims to design a flexible curriculum for children with special needs (ABK) at Pangudi Luhur Vincentius Kindergarten by taking into account the individual characteristics and potential development needs of each child.
Wulandari Kusuma Widoningrum, Dini Rahmawati, Arri Handayani   +2 more
doaj   +1 more source

Compatibility between Independent Activities in the Course of Study for Schools for Special Needs Education and ICF Categories [PDF]

, 2012
In the 2009 amendment to the course of study for schools for special needs education, the new teaching guideline "independent activities" was introduced to teach skills that ease difficulties in learning and daily living.
Mikami Fumiaki, Mita Takehiko, Okada Mihoko   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Competence of Shadow Teacher in Building Confidence and Life Skills of Students with Special Needs

Al-Adzka: Jurnal Ilmiah Pendidikan Guru Madrasah Ibtidaiyah
This study aims to describe the competencies of shadow teachers in developing the confidence and life skills of children with special needs at elementary school.
Ahmad Sahnan, Wahyu Purwasih, Novan Ardy Wiyani   +2 more
doaj   +1 more source

Inclusion of Pupils with SENs into Mainstream Physical Education – Potential Research Ideas to Explore Issues of Engagement [PDF]

, 2012
One consequence of the 1981 Education Act (DES, 1981) was that there began a transference of pupils from special educational schools to mainstream schools over the coming years.
Maher, Anthony, Palmer, Clive Alan
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source