Results 71 to 80 of about 308,507 (245)

Dutch decision as rooted in Dutch culture: An ethnologic study of the Dutch decision process [PDF]

open access: yes
Consensus is a mode of regulation well adapted to globalisation as it provides a means to reach agreements and manage diversity at the same time. However, is it a universal decision mode?
Jacqueline De Bony
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Societies Within: Selfhood through Dividualism & Relational Epistemology [PDF]

open access: yes
Most see having their individuality stifled as equivalent to the terrible forced conformity found within speculative fiction like George Orwell's 1984.
Morgan, Jonathan
core  

Volume 12, Number 5 - March 1932 [PDF]

open access: yes, 1932
Volume 12, Number 5 – March 1932. 26 pages including covers and advertisements. Who\u27s Who in the Alembic Cox, John F. Friend of New Ireland McDonough, John Alcaics for March LaCroix, John Good Friday Shunney, Walter J. Tax Gathering Murray,

core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The role of youth in solving problems of the country [PDF]

open access: yes, 2015
Before the Kyrgyz Republic faces the diffi cult task of modernization and development. One of the main resources of these tasks would be to involve young people in the solution of these problems. At the heart of democracy in the West, largely support the
Suyunbaev, M. N.
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

The Moderating Effects of Power Distance and Individualism/Collectivism on Empowering Leadership, Psychological Empowerment, and Self-Leadership in International Development Organizations

open access: yes, 2018
The importance of finding appropriate leadership styles to use in cross-cultural situations is paramount. Development organizations and multinational organizations both struggle to find forms of leadership that are effective in mobilizing the workforce ...
Rahschulte, Tim, Thomas, Debby
core  

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