Results 81 to 90 of about 169,269 (340)

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Propagation and antioxidative enzymes of Campanula velebitica Borbás grown in vitro [PDF]

, 2012
Background and purpose: Micropropagation possibility for Campanula velebitica Borbás (Campanulaceae), a rare Croatian endemic plant was studied. Additionally, the activity of several antioxidative enzymes, as biomarkers of stress conditions, was ...
BISERKA JELENČIĆ, MIRTA TKALEC, VANJA STAMENKOVIĆ   +2 more
core   +1 more source

Plant growth regulators induced urease activity in Cucurbita pepo L. cotyledons [PDF]

, 2016
This study is aimed to investigate the activity of urease (EC 3.5.1.5, urea amidohydrolase) that catalyzes the hydrolysis of urea in 5-day-old Cucurbita pepo cotyledons subjected to various concentrations of different growth regulators.
Ali, Awatif S., El Shora, Hamed M.
core   +1 more source

Isolasi dan karakterisasi senyawa metabolit sekunder dari bakteri laut Streptomyces sp.

Depik Jurnal, 2012
Streptomyces is one of bacterial genus which has been considered as a potential source of many novel antibiotics from both terrestrial and marinemicroorganism.
Muhammad bahi
doaj  

Optimization of indole-3-acetic acid production by Bacillus subtilis strain IA3

Ho Chi Minh City Open University Journal of Science - Engineering and Technology
Indole-3-Acetic Acid (IAA) is a crucial plant growth-promoting hormone produced as a secondary metabolite by various microorganisms. The present study aims to isolate and screen IAA-producing endospore-forming bacteria from soil samples collected in ...
Tuan Ngoc Nguyen, Linh Huynh Yen Luu
doaj   +1 more source

The Plant Growth-Promoting Rhizobacterium Variovorax boronicumulans CGMCC 4969 Regulates the Level of Indole-3-Acetic Acid Synthesized from Indole-3-Acetonitrile

Applied and Environmental Microbiology, 2018
We demonstrated that Variovorax boronicumulans CGMCC 4969 has two enzymatic systems—nitrilase and nitrile hydratase/amidase—that convert indole-3-acetonitrile (IAN) to the important plant hormone indole-3-acetic acid (IAA).
S. Sun, Wenlong Yang, Wen-Wan Fang, Yun-Xiu Zhao, Ling Guo, Yijun Dai   +5 more
semanticscholar   +1 more source

Metarhizium anisopliaeMitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source

Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice

eLife
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. There is growing evidence that dysbiosis of the intestinal microbiota and disruption of microbiota-host interactions contribute to the pathology of ...
Yufang Ding, Karin Yanagi, Fang Yang, Evelyn Callaway, Clint Cheng, Martha E Hensel, Rani Menon, Robert C Alaniz, Kyongbum Lee, Arul Jayaraman   +9 more
doaj   +1 more source

Feed interventions and skatole deposition [PDF]

, 2012
Skatole produced in the large intestine of the pig and the testicular steroid androstenone are the main substances contributing to boar tainted meat from entire male pigs.
Jensen, Rikke Lassen
core