Results 1 to 10 of about 44,366 (284)
Catalytic asymmetric formal nucleophilic C2-substitution of indoles via C2-umpolung toward 2,3’-bisindole atropisomers [PDF]
Nature CommunicationsThe electrophilic substitution of indoles represents the predominant functionalization strategy. However, due to the electron-rich nature of the indole scaffold, catalytic asymmetric nucleophilic substitution remains markedly underdeveloped—presenting ...
Cong-Hui Gao +6 more
doaj +2 more sources
Hexafluoroisopropanol Mediated Ring-Opening Reactions of Epoxides with Indoles Under Catalyst-Free Conditions [PDF]
MoleculesAn efficient, catalyst-free, and room-temperature protocol has been developed for the ring-opening reactions of ring cyclic ethers with indoles in Hexafluoroisopropanol (HFIP). Under these mild conditions, a diverse range of indoles smoothly reacted with
Yangmin Ma +5 more
doaj +2 more sources
Dual Role of Indoles Derived From Intestinal Microbiota on Human Health
Frontiers in Immunology, 2022 Endogenous indole and its derivatives (indoles), considered as promising N-substituted heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and exhibit a range of biological activities.
Xuewei Ye +9 more
doaj +1 more source
Green Synthesis and Catalysis, 2022 Chiral N-alkylated indoles are privileged structural motifs found in many natural products and pharmaceuticals and a search for effective methods with which to prepare chiral N-alkylated indoles is ongoing.
Xiaohua Li +4 more
doaj +1 more source
Aniline is an inducer, and not a precursor, for indole derivatives in Rubrivivax benzoatilyticus JA2. [PDF]
PLoS ONE, 2014 Rubrivivax benzoatilyticus JA2 and other anoxygenic photosynthetic bacteria produce indole derivatives when exposed to aniline, a xenobiotic compound. Though this phenomenon has been reported previously, the role of aniline in the production of indoles ...
Mohammed Mujahid +2 more
doaj +1 more source
Green Synthesis and Catalysis, 2021 A convenient method for the rapid construction of indolo[2,3-b]indoles has been developed. This cascade reaction involving condensation, dehydroaromatization, and oxidative annulation was achieved in a one-pot TMSI/DMSO system, providing a diversity of ...
Pingyu Jiang +5 more
doaj +1 more source
When Is an Indole Not an Indole? [PDF]
Clinical Chemistry, 1998 An indole is not an indole when it is a naphthalene derivative! We routinely measure 5-hydroxyindoleacetic acid (5HIAA) by a long-established method using nitrosonaphthol, as first described by Udenfriend in 1955 (1), but with various modifications to improve specificity (2).
Kathryn Brownbill, John A Martin
openaire +1 more source
Nano-Fe3O4 catalyzed synthesis of 3-aminoalkylated indoles and evaluation of their antibacterial activities [PDF]
شیمی کاربردی روز, 2014 Indoles are one of the most prevalent heterocyclic compounds, which are present as the basic cores in many natural products potent pharmaceutical compounds. Despite numerous diverse approaches toward the synthesis of indoles developed so far, it is still
Seyyedeh Cobra Azimi
doaj +1 more source
Ruthenium-Catalyzed Oxidative Synthesis of N-(2-triazine)indoles by C-H Activation
Molecules, 2023 1,3,5 triazines, especially indole functionalized triazine derivatives, exhibit excellent activities, such as anti-tumor, antibacterial, and anti-inflammatory activities.
Ming Zeng +7 more
doaj +1 more source
Microbiology Spectrum, 2022 The Gram-positive anaerobic bacterium Cutibacterium acnes is a major inhabitant of human skin and has been implicated in acne vulgaris formation and in the formation of multispecies biofilms with other skin-inhabiting organisms like Staphylococcus aureus
Yong-Guy Kim +3 more
doaj +1 more source