Results 31 to 40 of about 41,236 (276)
pi-Bond Directed C-2 Amination of Indoles: Catalysis Development, Mechanistic Investigation, and Substrate Scope [PDF]
, 2022 Cooperative functionalization of N-heterocycles, common motifs present in pharmaceuticals, agrochemicals, functional mate-rials, and natural products, is attractive but a challenging task.
Gregory, Cook +2 more
core +1 more source
IUCrData, 2021 The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham +3 more
doaj +1 more source
Direct Oxidative C-P Bond Formation of Indoles with Dialkyl Phosphites [PDF]
, 2012 The direct phosphonation of indoles was developed. In this reaction, dialkyl phosphites and indoles were used as substrates, and the C-P bond was formed through oxidative coupling mediated by silver(I) acetate.
Wu, Fan +4 more
core +1 more source
Green Halogenation of Indoles with Oxone-Halide [PDF]
, 2023 Oxidative functionalization of indoles is one of the most widely used approaches to exploit the synthetic utility of indoles. In continuation of our research interest in the green oxidation of indoles, we further explore the oxidation of indoles with ...
Ye, Jianghai +5 more
core +3 more sources
Crystals, 2023 The hit compound 1,2,4-triazolo[4’,3’:2,3]pyridazino[4,5-b]indole 3 was synthesized from the reflux of 4-amino-5-indolyl-1,2,4-triazole-3-thione 1 with 4′-bromoacetophenone 2 in methanol catalyzed by concentrated HCl and the desired final molecule was ...
Ahmed T. A. Boraei +5 more
doaj +1 more source
The benefits of indolence [PDF]
Communications of the ACM, 2019 The Communications Web site, http://cacm.acm.org, features more than a dozen bloggers in the BLOG@CACM community. In each issue of Communications , we'll publish selected posts or excerpts. twitter Follow us on Twitter at http://twitter ...
openaire +1 more source
, 1996 Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually.
Sundberg, Richard J.
core +2 more sources
Chemoselective N-acylation of indoles using thioesters as acyl source
Beilstein Journal of Organic Chemistry, 2022 The selective acylation of indoles often requires sensitive and reactive acyl chloride derivatives. Here, we report a mild, efficient, functional group tolerant, and highly chemoselective N-acylation of indoles using thioesters as a stable acyl source. A
Tianri Du +7 more
doaj +1 more source
Base-Promoted Tandem Synthesis of 2‑Substituted Indoles and N‑Fused Polycyclic Indoles [PDF]
, 2023 Herein is developed a base-promoted approach for the synthesis of C2-substituted indoles and N-fused polycyclic indoles via 5-endo-dig cyclization of 2-alkynyl anilines, followed by a 1,3′-acyl migration or a dearomatizing Michael addition process.
Fan Zhou +11 more
core +1 more source
Cascades to Substituted Indoles [PDF]
, 2016 This paper describes the synthesis of dithioindoles from the free-radical cyclizations of arylisonitriles having pendant alkynes. Also described is the synthesis of substituted indoles and spiro-fused indoles from the coupling of dithioindoles with ...
Jon D. Rainier (1688194) +1 more
core +3 more sources