Results 11 to 20 of about 44,366 (284)
Communications Chemistry, 2021 Dearomatisation of indoles allows efficient access to indolines, but often is incompatible with electron-withdrawing substituents. Here a photoredox Giese-type dearomatisation of indoles yields 2,3-disubstituted indolines bearing electron-withdrawing ...
Yueteng Zhang +7 more
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Undirected, Pd-catalysed deuteration of indoles with programmable regioselectivity [PDF]
, 2022 Methods for selective deuterium-incorporation into drug-like molecules have become extremely valuable due to the commercial and biological importance of deuterated compounds.
Rachael, McNulty +3 more
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BMC Plant Biology, 2023 Background Strobilanthes cusia (Nees) Kuntze is a traditional medical plant distributed widely in south China. The indole compounds that originated from the plant are responsible for its pharmacological activities.
Chang Liu +4 more
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Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities
Pharmaceutical Fronts, 2021 The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
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Programmable Deuteration of Indoles via Reverse Deuterium Exchange [PDF]
, 2023 Methods for selective deuterium incorporation into drug-like molecules have become extremely valuable due to the commercial, mechanistic, and biological importance of deuterated compounds.
Greener, Andrew +3 more
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Molecules, 2020 The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstituted
Xue Yan +4 more
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Recent Progress Concerning the N-Arylation of Indoles
Molecules, 2021 This review summarizes the current state-of-the-art procedures in terms of the preparation of N-arylindoles. After a short introduction, the transition-metal-free procedures available for the N-arylation of indoles are briefly discussed. Then, the nickel-
Petr Oeser +3 more
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SynOpen, 2023 The extensive range of uses of N-heterocycles as potent bioactive motifs has attracted researchers to expand newer methods for their efficient synthesis. Particularly, indoles are widely known for their prevalent pharmacological properties.
Kanaram Choupra +4 more
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Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles [PDF]
, 2022 The direct dearomative addition of arenes to the C3-position of unprotected indoles is reported under operationally simple condi-tions, using triflic acid at room temperature.
Vincent, Gandon +4 more
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Oxidative rearrangement of indoles to oxindoles [PDF]
, 2012 An unexpected oxidative rearrangement was observed when indoles substituted with 2-hydroxymalonates were subjected to typical iodination conditions.
Rodriguez, Arantxa +2 more
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