Results 11 to 20 of about 41,075 (284)
, 2018 Embedded medium-sized carbacycles and cyclohepta [b] indoles occur frequently as scaffold elements in natural products and bioactive compounds. Described herein is a conceptionally novel photochemically triggered cascade process to these scaffolds.
Tymann, Dina Christina +11 more
core +2 more sources
When Is an Indole Not an Indole? [PDF]
Clinical Chemistry, 1998 An indole is not an indole when it is a naphthalene derivative! We routinely measure 5-hydroxyindoleacetic acid (5HIAA) by a long-established method using nitrosonaphthol, as first described by Udenfriend in 1955 (1), but with various modifications to improve specificity (2).
Kathryn Brownbill, John A Martin
openaire +1 more source
BMC Plant Biology, 2023 Background Strobilanthes cusia (Nees) Kuntze is a traditional medical plant distributed widely in south China. The indole compounds that originated from the plant are responsible for its pharmacological activities.
Chang Liu +4 more
doaj +1 more source
Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities
Pharmaceutical Fronts, 2021 The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
doaj +1 more source
Molecules, 2020 The oxidative, dearomative cross-dehydrogenative coupling of indoles with various C-H nucleophiles is developed. This process features a broad substrate scope with respect to both indoles and nucleophiles, affording structurally diverse 2,2-disubstituted
Xue Yan +4 more
doaj +1 more source
SynOpen, 2023 The extensive range of uses of N-heterocycles as potent bioactive motifs has attracted researchers to expand newer methods for their efficient synthesis. Particularly, indoles are widely known for their prevalent pharmacological properties.
Kanaram Choupra +4 more
doaj +1 more source
Efficient copper-catalyzed synthesis of C3-alkylated indoles from indoles and alcohols
, 2021 A highly efficient copper(II) catalyst system for alkylation of indoles with alcohols via hydrogen borrowing method has been developed to afford C3-alkylated indoles in good to excellent yields. Cu(OAc)2 in the combination with dppm ligand has been found
Van Phuc, Ban +6 more
core +1 more source
Marine Drugs, 2015 Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in ...
Netz, Natalie, Opatz, Till
openaire +4 more sources
, 2022 Establishing three-dimensional chemicals by using the C2–C3 π bond of indoles has always been a research hotspot in organic synthesis; however, employing the oxidative C2–C3 π bond of indoles to generate imine which would lead to the N1–C2 π bond ...
Kui Du (3488084) +6 more
core +1 more source
Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles
Data in Brief, 2021 The data presented here are related to the research paper entitled “Efficient Synthesis of Cyano-containing Multi-substituted Indoles Catalyzed by Lipase” [1].
Fengxi Li +5 more
doaj +1 more source