Results 21 to 30 of about 45,952 (286)
Efficient copper-catalyzed synthesis of C3-alkylated indoles from indoles and alcohols
, 2021 A highly efficient copper(II) catalyst system for alkylation of indoles with alcohols via hydrogen borrowing method has been developed to afford C3-alkylated indoles in good to excellent yields. Cu(OAc)2 in the combination with dppm ligand has been found
Van Phuc, Ban +20 more
core +1 more source
Data for the lipase catalyzed synthesis of cyano-containing multi-substituted indoles
Data in Brief, 2021 The data presented here are related to the research paper entitled “Efficient Synthesis of Cyano-containing Multi-substituted Indoles Catalyzed by Lipase” [1].
Fengxi Li +5 more
doaj +1 more source
Molecules, 2022 This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series.
Ainur D. Sharapov +11 more
doaj +1 more source
Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C–H activation
Green Synthesis and Catalysis, 2021 The construction of indole, indoline and carbazole heterocycles has been of significant interest in the synthetic community over the last century due to their prevalence in natural products and other biologically active compounds.
Alexander J. Rago, Guangbin Dong
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2022 Indole-3,4- and 4,5-fused carbo- and heterocycles are ubiquitous in bioactive natural products and pharmaceuticals, and hence, a variety of synthetic approaches toward such compounds have been developed.
Jonali Das, Sajal Kumar Das
doaj +1 more source
Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles [PDF]
, 2022 The direct dearomative addition of arenes to the C3-position of unprotected indoles is reported under operationally simple condi-tions, using triflic acid at room temperature.
Vincent, Gandon +4 more
core +1 more source
Synthesis of pyrrolobenzothiadiazepines, pyrrolizidines and indoles [PDF]
In this thesis, novel syntheses of analogues of pyrrolobenzodiazepines (PBDs) are described. These compounds are of great interest as synthetic targets due to their potential medical properties.
Joãoa, Heidi
core +3 more sources
One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles
Molecules, 2022 A highly efficient and expeditious one-pot approach towards 2-(3-oxoindolin-2-yl)acetonitriles was designed, which involves a base-assisted aldol reaction of ortho-nitroacetophenones, followed by hydrocyanation, triggering an unusual reductive ...
Nicolai A. Aksenov +7 more
doaj +1 more source
Natural Product Reports, 2013 The natural product sesquiterpenyl indoles are structural hybrids from farnesyl pyrophosphate and tryptophan or its precursors, often with unusual and complex structural features, many of them with interesting biological activities. In this review the compounds of this class known until now are classified, a biosynthetic approach of each group is ...
Marcos, Isidro S. +4 more
openaire +3 more sources
A Novel C3/C4-Fused Indole Scaffold through Acid-Catalyzed Cascade Reaction
Molecules3,4-bridged indoles are underrepresented among the vast number of indoles described in the literature. Attempts to access 3,4-macrocyclized indoles led to the unexpected formation of a novel tetracyclic indole through intramolecular acid-catalyzed ring ...
Felix Potlitz +5 more
doaj +1 more source