Results 21 to 30 of about 41,075 (284)
Molecules, 2022 This paper reports the synthesis of four types of annulated pyranoindole congeners: pyrano[3,2-f]indole, pyrano[2,3-g]indole, pyrano[2,3-f]indole, and pyrano[2,3-e]indole and photophysical studies in this series.
Ainur D. Sharapov +11 more
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Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C–H activation
Green Synthesis and Catalysis, 2021 The construction of indole, indoline and carbazole heterocycles has been of significant interest in the synthetic community over the last century due to their prevalence in natural products and other biologically active compounds.
Alexander J. Rago, Guangbin Dong
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Programmable Deuteration of Indoles via Reverse Deuterium Exchange
, 2023 Methods for selective deuterium incorporation into drug-like molecules have become extremely valuable due to the commercial, mechanistic, and biological importance of deuterated compounds.
Greener, Andrew +3 more
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Natural Product Reports, 2013 The natural product sesquiterpenyl indoles are structural hybrids from farnesyl pyrophosphate and tryptophan or its precursors, often with unusual and complex structural features, many of them with interesting biological activities. In this review the compounds of this class known until now are classified, a biosynthetic approach of each group is ...
Marcos, Isidro S. +4 more
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New Approaches to Indoles and Indole Alkaloids [PDF]
Proceedings of the 14th Brazilian Meeting on Organic Synthesis Proceedings, 2013 Second only to pyridines, indoles are among the most common aromatic scaffolds present in bioactive molecules. The 5-hydroxy indole moiety alone has currently >10,500 substructure hits Among the many indole-containing alkaloid scaffolds, ergot alkaloids comprise a notable group of natural products of great biological activities. The striking biological
Peter Wipf, Filip Petronijevic
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Beilstein Journal of Organic Chemistry, 2022 Indole-3,4- and 4,5-fused carbo- and heterocycles are ubiquitous in bioactive natural products and pharmaceuticals, and hence, a variety of synthetic approaches toward such compounds have been developed.
Jonali Das, Sajal Kumar Das
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Undirected, Pd-catalysed deuteration of indoles with programmable regioselectivity
, 2022 Methods for selective deuterium-incorporation into drug-like molecules have become extremely valuable due to the commercial and biological importance of deuterated compounds.
Rachael, McNulty +3 more
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Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles
, 2022 The direct dearomative addition of arenes to the C3-position of unprotected indoles is reported under operationally simple condi-tions, using triflic acid at room temperature.
Vincent, Gandon +4 more
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IUCrData, 2021 The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham +3 more
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Crystals, 2023 The hit compound 1,2,4-triazolo[4’,3’:2,3]pyridazino[4,5-b]indole 3 was synthesized from the reflux of 4-amino-5-indolyl-1,2,4-triazole-3-thione 1 with 4′-bromoacetophenone 2 in methanol catalyzed by concentrated HCl and the desired final molecule was ...
Ahmed T. A. Boraei +5 more
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