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Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development.
Natalie Netz, Till Opatz
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Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities [PDF]
Novel secondary metabolites from marine macroorganisms and marine-derived microorganisms have been intensively investigated in the last few decades. Several classes of compounds, especially indole alkaloids, have been a target for evaluating biological ...
Joko Tri Wibowo +5 more
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Marine Indole Alkaloids—Isolation, Structure and Bioactivities [PDF]
Indole alkaloids are heterocyclic natural products with extensive pharmacological activities. As an important source of lead compounds, many clinical drugs have been derived from natural indole compounds.
Yong Hu +3 more
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Molecular cloning and functional characterization of BcTSA in the biosynthesis of indole alkaloids in Baphicacanthus cusia [PDF]
Baphicacanthus cusia (Nees) Bremek (B. cusia) is an essential traditional Chinese herb that is commonly used to treat colds, fever, and influenza. Indole alkaloids, such as indigo and indirubin, are the primary active constituents of B. cusia. The indole-
Zhiying Guo +7 more
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A Systematic Review of Analytical Methods for Quantification of Natural Indole Alkaloids from Catharanthus and Rauvolfia Species [PDF]
Indole alkaloids are a class of alkaloids enclosing a structural moiety of indole; numerous indole alkaloids also comprise isoprene groups and are thus named terpene indole or secologanin tryptamine alkaloids and have more than 4100 identified diverse ...
Lakshmipriya Murugesan +2 more
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Indole-Based Small Molecules as Potential Therapeutic Agents for the Treatment of Fibrosis
Indole alkaloids are widely distributed in nature and have been particularly studied because of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and anti-oxidant activities.
Rui Qin +7 more
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Indole alkaloids represent a large subset of natural products, with more than 4100 known compounds. The majority of these alkaloids are biologically active, with some exhibiting excellent antitumor, antibacterial, antiviral, antifungal, and ...
Syed Muhammad Umer +3 more
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Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities
The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
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A laboratory prototype of enzyme biosensor based on pH‐sensitive field‐effect transistors has been created to determine the total content of indole alkaloids in Rauwolfia serpentina tissue culture.
Valentyna Arkhypova +5 more
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Phytochemical investigation of the dichloromethane crude extract from the bark of Ochreinauclea maingayi with the aid of LCMS/MS-based molecular networking guided the isolation and accelerated the elucidation of known and new indole alkaloids.
Norfaizah Osman +9 more
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