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Marine Indole Alkaloids [PDF]

open access: yesMarine Drugs, 2015
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development.
Natalie Netz, Till Opatz
doaj   +4 more sources

Marine-Derived Indole Alkaloids and Their Biological and Pharmacological Activities [PDF]

open access: yesMarine Drugs, 2021
Novel secondary metabolites from marine macroorganisms and marine-derived microorganisms have been intensively investigated in the last few decades. Several classes of compounds, especially indole alkaloids, have been a target for evaluating biological ...
Joko Tri Wibowo   +5 more
doaj   +2 more sources

Marine Indole Alkaloids—Isolation, Structure and Bioactivities [PDF]

open access: yesMarine Drugs, 2021
Indole alkaloids are heterocyclic natural products with extensive pharmacological activities. As an important source of lead compounds, many clinical drugs have been derived from natural indole compounds.
Yong Hu   +3 more
doaj   +2 more sources

Molecular cloning and functional characterization of BcTSA in the biosynthesis of indole alkaloids in Baphicacanthus cusia [PDF]

open access: yesFrontiers in Plant Science, 2023
Baphicacanthus cusia (Nees) Bremek (B. cusia) is an essential traditional Chinese herb that is commonly used to treat colds, fever, and influenza. Indole alkaloids, such as indigo and indirubin, are the primary active constituents of B. cusia. The indole-
Zhiying Guo   +7 more
doaj   +2 more sources

A Systematic Review of Analytical Methods for Quantification of Natural Indole Alkaloids from Catharanthus and Rauvolfia Species [PDF]

open access: yesResearch Journal of Pharmacognosy, 2023
Indole alkaloids are a class of alkaloids enclosing a structural moiety of indole; numerous indole alkaloids also comprise isoprene groups and are thus named terpene indole or secologanin tryptamine alkaloids and have more than 4100 identified diverse ...
Lakshmipriya Murugesan   +2 more
doaj   +1 more source

Indole-Based Small Molecules as Potential Therapeutic Agents for the Treatment of Fibrosis

open access: yesFrontiers in Pharmacology, 2022
Indole alkaloids are widely distributed in nature and have been particularly studied because of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and anti-oxidant activities.
Rui Qin   +7 more
doaj   +1 more source

Indole-Containing Natural Products 2019–2022: Isolations, Reappraisals, Syntheses, and Biological Activities

open access: yesMolecules, 2022
Indole alkaloids represent a large subset of natural products, with more than 4100 known compounds. The majority of these alkaloids are biologically active, with some exhibiting excellent antitumor, antibacterial, antiviral, antifungal, and ...
Syed Muhammad Umer   +3 more
doaj   +1 more source

Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities

open access: yesPharmaceutical Fronts, 2021
The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
doaj   +1 more source

Enzyme biosensor based on pH‐sensitive field‐effect transistors for assessment of total indole alkaloids content in tissue culture of Rauwolfia serpentina

open access: yesElectrochemical Science Advances, 2022
A laboratory prototype of enzyme biosensor based on pH‐sensitive field‐effect transistors has been created to determine the total content of indole alkaloids in Rauwolfia serpentina tissue culture.
Valentyna Arkhypova   +5 more
doaj   +1 more source

Isolation and Characterization of Compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the Aid of LCMS/MS Molecular Networking

open access: yesSeparations, 2023
Phytochemical investigation of the dichloromethane crude extract from the bark of Ochreinauclea maingayi with the aid of LCMS/MS-based molecular networking guided the isolation and accelerated the elucidation of known and new indole alkaloids.
Norfaizah Osman   +9 more
doaj   +1 more source

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