Results 11 to 20 of about 13,686 (198)
Indole Alkaloids as Biased Opioid Receptor Modulators [PDF]
PharmaceuticalsBackground: Opioid receptors are a commonly used target for treatment of pain conditions. Most opioids used in therapy are linked to adverse effects such as tolerance, dependence, and respiratory depression.
Oliver Grundmann, Allison Henderson
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Identification of Filovirus Entry Inhibitors from Marine Fungus-Derived Indole Alkaloids [PDF]
Marine DrugsFiloviruses, mainly consisting of the two genera of Ebolavirus and Marburgvirus, are enveloped negative-strand RNA viruses that can infect humans to cause severe hemorrhagic fevers and outbreaks with high mortality rates.
Leah Liu Wang +6 more
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Modular assembly of indole alkaloids enabled by multicomponent reaction [PDF]
Nature Communications, 2023 Indole alkaloids are one of the largest alkaloid classes, proving valuable structural moiety in pharmaceuticals. Although methods for the synthesis of indole alkaloids are constantly explored, the direct single-step synthesis of these chemical entities ...
Jiaming Li +4 more
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Indole Alkaloids from Psychoactive Mushrooms: Chemical and Pharmacological Potential as Psychotherapeutic Agents [PDF]
Biomedicines, 2023 Neuropsychiatric diseases such as depression, anxiety, and post-traumatic stress represent a substantial long-term challenge for the global health systems because of their rising prevalence, uncertain neuropathology, and lack of effective pharmacological
Erika Plazas, Nicoletta Faraone
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Biosynthesis of fungal indole alkaloids [PDF]
Nat. Prod. Rep., 2014 This review provides a summary of recent research advances in elucidating the biosynthesis of fungal indole alkaloids.
Xu, Wei, Gavia, Diego J, Tang, Yi
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Marine Drugs, 2010 This paper presents the alkaloids found in green, brown and red marine algae. Algal chemistry has interested many researchers in order to develop new drugs, as algae include compounds with functional groups which are characteristic from this particular ...
Ekrem Sezik +2 more
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Biosynthesis of the indole and colchicum alkaloids [PDF]
Pure and Applied Chemistry, 1967 Abstract
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Rigorous Biogenetic Network for a Group of Indole Alkaloids Derived from Strictosidine
Molecules, 2008 : Strictosidine, the precursor of more than 2,500 indole alkaloids, was isolated from four species of three plant families. By searching the Dictionary of Natural Products on DVD it was found that about 150 indole alkaloids were obtained from the same ...
László F. Szabó
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Cardiovascular diseases are the most common human diseases, hence, the production of cardiological (in particular, anti-arrhythmic) medications from the natural sources is an ever-actual task. Rauwolfia serpentina Benth.
O. A. Bieda +5 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source