Results 21 to 30 of about 31,700 (240)

A Systematic Review of Analytical Methods for Quantification of Natural Indole Alkaloids from Catharanthus and Rauvolfia Species [PDF]

open access: yesResearch Journal of Pharmacognosy, 2023
Indole alkaloids are a class of alkaloids enclosing a structural moiety of indole; numerous indole alkaloids also comprise isoprene groups and are thus named terpene indole or secologanin tryptamine alkaloids and have more than 4100 identified diverse ...
Lakshmipriya Murugesan   +2 more
doaj   +1 more source

Indole-Based Small Molecules as Potential Therapeutic Agents for the Treatment of Fibrosis

open access: yesFrontiers in Pharmacology, 2022
Indole alkaloids are widely distributed in nature and have been particularly studied because of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and anti-oxidant activities.
Rui Qin   +7 more
doaj   +1 more source

Indole-Containing Natural Products 2019–2022: Isolations, Reappraisals, Syntheses, and Biological Activities

open access: yesMolecules, 2022
Indole alkaloids represent a large subset of natural products, with more than 4100 known compounds. The majority of these alkaloids are biologically active, with some exhibiting excellent antitumor, antibacterial, antiviral, antifungal, and ...
Syed Muhammad Umer   +3 more
doaj   +1 more source

Natural Indole Alkaloids from Marine Fungi: Chemical Diversity and Biological Activities

open access: yesPharmaceutical Fronts, 2021
The indole scaffold is one of the most important heterocyclic ring systems for pharmaceutical development, and serves as an active moiety in several clinical drugs.
Jiao Li, Chun-Lin Zhuang
doaj   +1 more source

Isolation and Characterization of Compounds from Ochreinauclea maingayi (Hook. f.) Ridsd. (Rubiaceae) with the Aid of LCMS/MS Molecular Networking

open access: yesSeparations, 2023
Phytochemical investigation of the dichloromethane crude extract from the bark of Ochreinauclea maingayi with the aid of LCMS/MS-based molecular networking guided the isolation and accelerated the elucidation of known and new indole alkaloids.
Norfaizah Osman   +9 more
doaj   +1 more source

Enzyme biosensor based on pH‐sensitive field‐effect transistors for assessment of total indole alkaloids content in tissue culture of Rauwolfia serpentina

open access: yesElectrochemical Science Advances, 2022
A laboratory prototype of enzyme biosensor based on pH‐sensitive field‐effect transistors has been created to determine the total content of indole alkaloids in Rauwolfia serpentina tissue culture.
Valentyna Arkhypova   +5 more
doaj   +1 more source

Phytochemical characterization of Tabernanthe iboga root bark and its effects on dysfunctional metabolism and cognitive performance in high-fat-fed C57BL/6J mice [PDF]

open access: yes, 2018
Preparations of the root bark of Tabernanthe iboga have long been used in Central and West African traditional medicine to combat fatigue, as a neuro-stimulant in rituals, and for treatment of diabetes. The principal alkaloid of T.
Akinyeke, Tunde   +11 more
core   +2 more sources

Indole diterpenoid natural products as the inspiration for new synthetic methods and strategies. [PDF]

open access: yes, 2017
Indole terpenoids comprise a large class of natural products with diverse structural topologies and a broad range of biological activities. Accordingly, indole terpenoids have and continue to serve as attractive targets for chemical synthesis.
Corsello, Michael A   +2 more
core   +1 more source

Determination of content of indole alkaloids in cell biomass of Rauwolfia serpentina Benth. ex Kurz tissue culture

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
Cardiovascular diseases are the most common human diseases, hence, the production of cardiological (in particular, anti-arrhythmic) medications from the natural sources is an ever-actual task. Rauwolfia serpentina Benth.
O. A. Bieda   +5 more
doaj   +1 more source

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