Results 31 to 40 of about 13,686 (198)
Advanced Science, EarlyView.Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou +6 more
wiley +1 more source
Two New Cytotoxic Indole Alkaloids from a Deep-Sea Sediment Derived Metagenomic Clone
Marine Drugs, 2014 Two new indole alkaloids, metagenetriindole A (1) and metagenebiindole A (2), were identified from deep-sea sediment metagenomic clone derived Escherichia coli fermentation broth.
Xia Yan +6 more
doaj +1 more source
Structural Elucidation and Cytotoxic Activity of New Monoterpenoid Indoles from Gelsemium elegans
Molecules, 2023 Two new monoterpenoid indole alkaloids, gelselegandines F (1) and G (2), were isolated from the aerial parts of Gelsemium elegans. Their structures were elucidated by means of spectroscopic techniques and quantum chemical calculations.
Da Song +10 more
doaj +1 more source
Indole Alkaloids of Ailanthus altissima
Journal of Natural Products, 1984 Ailanthus altissima (Mill.) Swingle, Syn. A. glandulosa Desf. (Simaroubaceae), is a large tree indigenous to China. It is known as the “Tree of Heaven” and has been the subject of several chemical studies. The presence of quassinoid-type bitter principles (1-6), flavonols (7,8), and 2,6-dimethoxy-p-benzoquinone (9,10) has been reported in earlier ...
Souleles, C., Waigh, R.
openaire +2 more sources
Toxins, 2016 Different group of alkaloids are produced during the symbiotic development of fungal endophytes of the genus Epichloë in grass. The structure and toxicity of the compounds vary considerably in mammalian herbivores and in crop pests.
Guerre Philippe
doaj +1 more source
N‐Aryl Acridone Derivatives as Effective Catalysts for Energy Transfer Reactions
Chemistry – A European Journal, EarlyView.Acridones derivatives have high triplet energy, are simple accessible, and could be used in challenging [2+2] ENT reactions. ABSTRACT Organic photocatalysts capable of promoting high‐energy triplet energy transfer (EnT) remain limited, particularly for demanding [2+2] photocycloaddition reactions.
Francesco Calogero +8 more
wiley +1 more source
Secondary Metabolites from Rubiaceae Species
Molecules, 2015 This study describes some characteristics of the Rubiaceae family pertaining to the occurrence and distribution of secondary metabolites in the main genera of this family. It reports the review of phytochemical studies addressing all species of Rubiaceae,
Daiane Martins, Cecilia Veronica Nunez
doaj +1 more source
Chemistry – A European Journal, EarlyView.Several new chiral cyclic hypervalent iodine(III) reagents have been synthesized and characterized. Carbon‐based ligands were successfully installed onto the hypervalent iodine centers, giving thus access to novel chiral cyano‐, trifluoromethyl‐ or alkynyl‐bearing λ3‐iodanes.
Emmanuel Valzer +4 more
wiley +1 more source
Ullmann‐Type N‐Heteroarylation of Nitrogen Heterocycles Catalyzed by Heterogeneous CuNPs/HKUST‐1
EcoEnergy, EarlyView.A practical strategy for the direct synthesis of CuNPs/HKUST‐1 heterogeneous catalyst was developed and used for the catalyzing Ullmann‐type N‐arylation of N‐heterocycles with high yields, excellent recyclability, and low copper leaching. ABSTRACT Ullmann‐type C–N coupling is an essential reaction to construct functional nitrogen heterocycles, whereas ...
Shuai Yang +9 more
wiley +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, EarlyView.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source