Results 51 to 60 of about 41,075 (284)

Green Halogenation of Indoles with Oxone-Halide

, 2023
Oxidative functionalization of indoles is one of the most widely used approaches to exploit the synthetic utility of indoles. In continuation of our research interest in the green oxidation of indoles, we further explore the oxidation of indoles with ...
Ye, Jianghai, Xu, Jun, Ma, Shiqiang, Zheng, Tao, Tong, Rongbiao, Cheng, Shaojun   +5 more
core   +2 more sources

Development of an imidazole salt catalytic system for the preparation of bis(indolyl)methanes and bis(naphthyl)methane.

PLoS ONE, 2019
Imidazolium salts are shown to catalyze the rapid room temperature reaction of indoles or naphthol with aldehydes to provide bis(indolyl)methanes or bis(naphthol)methane in excellent yields and the reaction proceeds optimally in dichloromethane with no ...
Xu Wang, Courtney C Aldrich
doaj   +1 more source

Síntese ambientalmente adequada de 3-selenil-indóis [PDF]

, 2014
(Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2014No presente trabalho desenvolveu-se uma nova metodologia sintética ambientalmente ...
Ferreira, Natasha Londero
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Caper (Capparis spinosa L.): An Updated Review on Its Phytochemistry, Nutritional Value, Traditional Uses, and Therapeutic Potential

Frontiers in Pharmacology, 2022
Caper (Capparis spinosa L.) is a perennial shrub of the family Capparaceae, endemic to circum-Mediterranean countries. Caper carries a renowned nutritional value, especially in terms of vitamins and antioxidants related to the occurrence of flavonoids ...
Hassan Annaz, Yaya Sane, Gabin Thierry M. Bitchagno, Widad Ben Bakrim, Widad Ben Bakrim, Badreddine Drissi, Ismail Mahdi, Mustapha El Bouhssini, Mansour Sobeh   +8 more
doaj   +1 more source

3-Alkylated indoles by reduction of sulfonyl indoles under flow chemical conditions [PDF]

, 2019
Reduction of 3-(1-arylsulfonylalkyl) indoles (sulfonyl indoles) using polymer-supported sodium borohydride under flow chemical conditions allows an efficient synthesis of 3-alkylindoles with a notable waste minimization and reduced solvent consumption.
Alessandro Palmieri, Marino Petrini, Elena Chiurchiù   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Indoles /

, 1996
Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually.
Sundberg, Richard J.
core   +1 more source

Synthesis of Indole Derivatives via Aryl Triazole Ring-Opening and Subsequent Cyclization

Molecules
A metal-free two-step synthetic approach for obtaining indole derivatives from aryl triazole fragment-containing compounds has been developed. In the first step, the Dimroth equilibrium, followed by nitrogen extrusion, Wolff rearrangement, and amine ...
Aleksejs Burcevs, Armands Sebris, Irina Novosjolova, Anatoly Mishnev, Māris Turks   +4 more
doaj   +1 more source

Diversity‐Oriented Catalytic Asymmetric Dearomatization of Indoles with o‐Quinone Diimides

Advanced Science, 2023
Herein, the first diversity‐oriented catalytic asymmetric dearomatization of indoles with o‐quinone diimides (o‐QDIs) is reported. The catalytic asymmetric dearomatization (CADA) of indoles is one of the research focuses in terms of the structural and ...
Hao‐Jie Gao, Yu‐Hang Miao, Wen‐Na Sun, Rui Zhao, Xiao Xiao, Yuan‐Zhao Hua, Shi‐Kun Jia, Min‐Can Wang, Guang‐Jian Mei   +8 more
doaj   +1 more source