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Toxicology and Analysis of Psychoactive Tryptamines [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Our understanding of tryptamines is poor due to the lack of data globally. Tryptamines currently are not part of typical toxicology testing regimens and their contribution to drug overdoses may be underestimated. Although their prevalence was low, it is increasing.
Alfredo Fabrizio Lo Faro   +2 more
exaly   +3 more sources

The toxicology and characteristics of fatal new psychoactive stimulant and hallucinogen-related poisonings in Australia, 2000–2025 [PDF]

open access: yesDrug and Alcohol Dependence Reports
Background: New psychoactive stimulants and hallucinogens (NPSH) poisonings have generated considerable public health concern in recent years. We aimed to determine: 1.
Shane Darke   +4 more
doaj   +2 more sources

Hallucinogen use in the United States, 2021–2023: Diverging trends and subgroup patterns [PDF]

open access: yesDrug and Alcohol Dependence Reports
Background: While interest in the therapeutic and recreational use of hallucinogens has increased, national surveillance often reports use in aggregate, potentially masking shifting trends among pharmacologically distinct substances.
Jing-Jer Chen   +2 more
doaj   +2 more sources

Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives [PDF]

open access: yesPharmaceuticals
The Psilocybe genus is known for producing tryptamine alkaloids, specifically the compounds psilocybin and psilocin, which have shown antidepressant and anxiolytic potential.
Mateus A. Luz   +10 more
doaj   +2 more sources

A sustainable protocol for the synthesis of N-acyl tryptamines, a class of potential gut microbiota-derived endocannabinoid-like mediators [PDF]

open access: yesFrontiers in Chemistry
A simple and sustainable propylphosphonic anhydride (T3P)-assisted methodology for the synthesis of N-acyl tryptamines, an interesting class of gut microbiota-derived endocannabinoid-like lipid mediators, was proposed.
Rosaria Villano   +2 more
doaj   +2 more sources

Determination of Three Types of New Psychoactive Tryptamines in Blood by QuEChERS Combined with UPLC-MS/MS [PDF]

open access: yesFayixue Zazhi, 2021
Objective To establish a method combining QuEChERS and ultra-high liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for rapid screening and testing of three types of new psychoactive tryptamines in human blood: 5-MeO-DALT, 5-MeO-MiPT and 5-MeO ...
HOU Wei, WANG Yan-yan, ZHANG Ying, et al.
doaj   +1 more source

Determination of tryptamine analogs in whole blood by 96-well electromembrane extraction and UHPLC-MS/MS

open access: yesTalanta Open, 2023
Tryptamines are a class of new psychoactive substances relevant for analysis in forensic laboratories. Tryptamine analogs are diverse in structure and chemical properties, and prone to display instability.
Maria Schüller   +4 more
doaj   +1 more source

Bufotenidinium iodide

open access: yesIUCrData, 2021
The title compound, 5-hydroxy-N,N,N-trimethyltryptammonium (5-HTQ) iodide {systematic name: [2-(5-hydroxy-1H-indol-3-yl)ethyl]trimethylazanium iodide}, C13H19N2O+·I−, has a single tryptammonium cation and one iodide anion in the asymmetric unit. The ions
Duyen N. K. Pham   +3 more
doaj   +1 more source

Bis(4-acetoxy-N-ethyl-N-n-propyltryptammonium) fumarate–fumaric acid (1/1)

open access: yesIUCrData, 2023
The solid-state structure of the title salt/adduct (systemic name: bis{[2-(4-acetyloxy-1H-indol-3-yl)ethyl](ethyl)propylazanium} but-2-enedioate–(E)-butenedioic acid (1/1)), 2C17H25N2O2+·C4H2O42−·C4H4O4, was determined by single-crystal X-ray diffraction.
Duyen N. K. Pham   +4 more
doaj   +1 more source

A Review of Synthetic Access to Therapeutic Compounds Extracted from Psilocybe

open access: yesPharmaceuticals, 2022
Psychedelics are used for various pathologies of the central nervous system and are currently the subject of much research, some of which relates to the compounds contained in various Psilocybe-type hallucinogenic mushrooms.
Raphaël Serreau   +3 more
doaj   +1 more source

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