Results 41 to 50 of about 3,690 (207)

Quaternary tryptammonium salts: N,N-dimethyl-N-n-propyltryptammonium (DMPT) iodide and N-allyl-N,N-dimethyltryptammonium (DMALT) iodide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
The solid-state structures of two quaternary trytpammonium salts, namely, N,N-dimethyl-N-n-propyltryptammonium (DMPT) iodide [systematic name: 2-(1H-indol-3-yl)-N,N-dimethyl-N-propylazanium iodide], C15H23N2+·I−, and N-allyl-N,N-dimethyltryptammonium ...
Andrew R. Chadeayne   +3 more
doaj   +1 more source

Organocatalytic asymmetric synthesis of bioactive hexahydropyrrolo[2,3-b]indole-containing tetrasubstituted allenes bearing multiple chiral elements

open access: yesTetrahedron Chem, 2022
An organocatalytic asymmetric construction of hexahydropyrrolo[2,3-b]indole-containing tetrasubstituted allene scaffolds bearing both axial chirality and central chirality has been established via a cascade 1,8-addition/dearomatization-cyclization ...
Jing-Yi Wang   +7 more
doaj   +1 more source

Synthesis of Chiral Tryptamines via a Regioselective Indole Alkylation

open access: yes, 2018
A practical synthesis of chiral tryptamines from simple, unprotected indoles has been developed. Indole nucleophiles prepared with MeMgCl in the presence of CuCl reacted with chiral cyclic sulfamidates almost exclusively at the C3-position of indole to ...
Jens Wolfard   +7 more
core   +2 more sources

Correlation of Tryptamine-Induced Convulsions in Rats with Brain Tryptamine Concentration

open access: yesExperimental Biology and Medicine, 1960
SummaryNormal rat brain tryptamine concentration was 0.032 ± 0.002 μg/g (mean ± S.E.M.). Oral administration of 0.72 mg/ kg of tranylcypromine (trans 2-phenylcyclopropylamine) or 25 mg/kg of iproniazid (1-isonicotinyl-2-isopropyl hydrazine) had no apparent effect upon normal rat brain tryptamine concentration. Sixty to 75 seconds after i.v.
H, GREEN, J L, SAWYER
openaire   +2 more sources

N-Methyl-N-propyltryptamine (MPT)

open access: yesIUCrData, 2019
The title compound {systematic name: [2-(1H-indol-3-yl)ethyl](methyl)propylamine}, C14H20N2, has a single molecule in the asymmetric unit. The molecules in the unit cell are held together in infinite one-dimensional chains along [010] through N—H...N ...
Andrew R. Chadeayne   +2 more
doaj   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler   +6 more
wiley   +1 more source

Intramolecular hydrogen bond in N-(2’-hydroxybenzyl)tryptamines.

open access: yes, 2019
Intramolecular hydrogen bond in N-(2’-hydroxybenzyl)tryptamines.
Miguel Toro-Sazo (6195353)   +4 more
core   +1 more source

Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production

open access: yesFrontiers in Immunology, 2021
The liver is the central hub for processing and maintaining homeostatic levels of dietary nutrients especially essential amino acids such as tryptophan (Trp).
Soumya R. Mohapatra   +15 more
doaj   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor   +11 more
wiley   +1 more source

Ni-Catalyzed Intermolecular Allylic Dearomatization Reaction of Tryptophols and Tryptamines

open access: yes, 2019
An efficient synthesis of pyrrolidinoindolines and tetrahydro­furanoindolines was achieved via Ni-catalyzed allylic dearomatization reactions of tryptophols and tryptamines.
Hui-Jun Zhang (1415167)   +2 more
core   +1 more source

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