Results 61 to 70 of about 5,094 (245)

Bis(4-acetoxy-N,N-dimethyltryptammonium) fumarate: a new crystalline form of psilacetin, an alternative to psilocybin as a psilocin prodrug

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compound (systematic name: bis{2-[4-(acetyloxy)-1H-indol-3-yl]ethan-1-aminium} but-2-enedioate), 2C14H19N2O2+·C4H2O42−, has a single protonated psilacetin cation and one half of a fumarate dianion in the asymmetric unit.
Andrew R. Chadeayne, James A. Golen, David R. Manke   +2 more
doaj   +1 more source

Multimodal Strategy for Efficient Semi‐Transparent Perovskite Solar Cells and Modules with Record Indoor Performance

Advanced Energy Materials, EarlyView.
A multimodal strategy creates efficient semi‐transparent perovskite solar cells with a record 4.29% light utilization efficiency and 22.41% indoor performance. This approach enables the first scalable 30 x 30 cm2 semi‐transparent solar module, highlighting its potential for building‐integrated and indoor photovoltaics.
Siming Huang, Shanyue Hou, Yuting Wang, Yinheng Ren, Yujie Wo, Jingdong Xu, Jinzhao Qin, Galyam Sanfo, Zahra Albu, Kai Qiu, Himal Muwanwella, Iona Hill, Yuelong Huang, Rebecca L. Milot, Xiang Liu, Muhammad Tariq Sajjad, Mojtaba Abdi‐Jalebi   +16 more
wiley   +1 more source

Construction of a predictive model for the design of triptamin analogues with potential activity in Parkinson's and Alzheimer's diseases

Informatics in Medicine Unlocked, 2023
A growing public health issue has been caused by the diagnosis of neurodegenerative pathologies in millions of people. These conditions are caused by the progressive degeneration of brain cells, which results in the loss of synaptic connections between ...
Santiago Pirela-Ocando, Ana Romero-Cabezas, James Guevara-Pulido   +2 more
doaj   +1 more source

Consecutive Four-Component Coupling-Addition Aza-Anellation Pictet–Spengler Synthesis of Tetrahydro-β-Carbolines: An Optimized Michael Addition and Computational Study on the Aza-Anellation Step

Organics, 2023
Starting from acid chlorides, alkynes, tryptamines, and acryloyl chloride, 21 densely substituted tetrahydro-β-carbolines were prepared in a four-component, one-pot reaction.
Kai Ries, Françoise A. Aouane, Thomas J. J. Müller   +2 more
doaj   +1 more source

Radikale Kaskadenreaktion, welche die Kreuzkupplung von Olefinen mit der Smiles‐Truce‐Umlagerung kombiniert

Angewandte Chemie, EarlyView.
Wir stellen eine kobaltkatalysierte Radikalkaskade vor, die zwei Alken Ausgangsstoffe effizient miteinander verbindet und so in einem einzigen Schritt mehrere Bindungen aufbaut. Der Prozess beginnt mit einem kobaltkatalysierten Wasserstoffatomtransfer an eine Styrol‐Doppelbindung, gefolgt von einer Giese‐Addition.
Jingyang Qin, Lucas Popek, Moritz Wyrtki, Christopher J. Teskey   +3 more
wiley   +1 more source

\u3cem\u3eIn Vitro\u3c/em\u3e Determination of Potency of Small Molecule Inhibitors of Arp2/3 Complex [PDF]

, 2019
Actin is a key protein building block of actin microfilaments, which are constructed and deconstructed in response to cellular signaling pathways to regulate cellular processes such as motility, division, and endocytosis.
Andersen, Katherine, Baggett, Andrew W., Cavas, Levent, Collins, Jordan, Cournia, Zoe, DeRocher, Shelby, Nolen, Brad J., Pierson, Christina, Wade, Natalie   +8 more
core   +1 more source

Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5- MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn, and LC-HR-MS/MS [PDF]

Many N,N-dialkylated tryptamines show psychoactive properties and were encountered as new psychoactive substances. The aims of the presented work were to study the phase I and II metabolism and the detectability in standard urine screening approaches ...
Brandt, SD, Caspar, AT, Gaab, JB, Maurer, HH, Meyer, MR, Michely, JA   +5 more
core   +1 more source

C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines [PDF]

, 2014
A versatile strategy for C7-selective boronation of tryptophans, tryptamines, and 3-alkylindoles by way of a single-pot C2/C7-diboronation–C2-protodeboronation sequence is described. The combination of a mild iridium-catalyzed C2/C7-diboronation followed
Amaike, Kazuma, Fenton, Owen S., Loach, Richard Peter, Movassaghi, Mohammad, Ozkal, Erhan, Siegel, Dustin Scott   +5 more
core   +2 more sources

Radical Cascade Combining Cross‐Olefin Coupling with the Smiles‐Truce Rearrangement

Angewandte Chemie International Edition, EarlyView.
We present a cobalt‐catalysed radical cascade that efficiently merges two alkene starting materials to form multiple bonds in a single step. The process begins with a cobalt‐catalysed hydrogen‐atom transfer‐to a styrene double bond, followed by a Giese addition.
Jingyang Qin, Lucas Popek, Moritz Wyrtki, Christopher J. Teskey   +3 more
wiley   +1 more source

In vitro monoamine oxidase inhibition potential of alpha- methyltryptamine analog new psychoactive substances for assessing possible toxic risks [PDF]

Tryptamines have emerged as new psychoactive substances (NPS), which are distributed and consumed recreationally without preclinical studies or safety tests.
Brandt, SD, Kavanagh, PV, Maurer, HH, Meyer, MR, Wagmann, L   +4 more
core   +1 more source