Results 71 to 80 of about 2,867 (194)

Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening

Angewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker, Meghan E. Campbell, Peyton M. Higgins, Andrew R. Buller   +3 more
wiley   +2 more sources

Electron‐Donating Multifunctional Molecules: A Strategy for High‐Performance Perovskite Solar Cells

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Multifunctional molecules containing electron‐donating groups are critically important in perovskite solar cells (PSCs), including defect passivation, crystallization modulation, energy level alignment, and other functions. This review systematically examines the application and research progress of such multifunctional molecules in PSCs ...
Heng Liu, Hongxing Yuan, Hanyu Guo, Wenhao Zhou, Zhaoqi Zhang, Hongfei Zhang, Suyang Sun, Yiming Zhu, Zhenghui Qiu, Zhiyuan Zhu, Pengfei Yue, Guoshang Zhang, Qiongqiong Lu, Weihai Zhang, Kexing Song   +14 more
wiley   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, Volume 293, Issue 15, Page 4533-4553, August 2026.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Support in the Shadows: Findings From a Qualitative Study Exploring Fathers’ and Non‐Birthing Partners’ Perceptions and Experiences of Support During a Termination for Medical Reasons

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Termination for medical reasons (TFMR) is an essential aspect of reproductive healthcare. While physical and emotional care of the birthing parent is central within healthcare systems, less is known about the experiences and support needs of non‐birthing partners during this process.
Sarah Fogarty, Kirstin Tindal, Alexander E. P. Heazell, Niki Munk, Frances M. Boyle, Phillipa Hay   +5 more
wiley   +1 more source

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling

Swiss Medical Weekly, 2015
Novel psychoactive substances are newly used designer drugs (“internet drugs”, “research chemicals”, “legal highs”) potentially posing similar health risks to classic illicit substances.
Matthias Liechti
doaj   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2787-2826, August 2026.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

Designer drugs: aspectos analíticos e biológicos

Química Nova, 2012
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão, Solange Cristina Garcia, Renata Pereira Limberger, Marília Baierle, Marcelo Dutra Arbo, Alice Aparecida da Matta Chasin, Flávia Valladão Thiesen, Rejane Tavares   +7 more
doaj   +1 more source

First Tetraploa Genome and Multi‐Omics Analysis Reveal Key Plant‐Microbe‐Soil Interactions for Salt Tolerance and Yield Improvement of Wheat

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4748-4765, August 2026.
ABSTRACT Salinity is a major threat to global agricultural productivity of staple crops such as wheat. Although microbial‐based solutions hold promise for alleviating salinity stress, practical implementation is hindered by insufficient mechanistic characterization of bioinoculants and their interactions with plants.
Cheng‐Wei Qiu, Shuo Zhang, Zi‐Feng Gao, Zhong‐Hua Chen, Chulong Zhang, Mohamed Abdelalim Ali, Feibo Wu   +6 more
wiley   +1 more source

Spatiotemporal Metabolome and Single‐Nucleus Transcriptome Integration Illuminates an Auxin Gradient Orchestrated by NtTAC1 Underlying Leaf Angle Regulation in Tobacco

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4897-4915, August 2026.
Proposed model of TAC1‐mediated leaf angle regulation in tobacco. ABSTRACT Plant architecture is key to crop yield, with leaf angle being critical for high‐density cultivation. Although TAC1 represents a promising regulator of leaf angle for breeding, its molecular mechanism remains poorly understood, particularly at single‐nucleus resolution. Here, we
Lin Wang, Junping Gao, Chen Wang, Guoyun Xu, Zhen Ma, Shuaibin Wang, Zhaopeng Luo, Mingzhu Wu, Jianfeng Zhang, Jun Yang, Peijian Cao, Xiaodong Xie   +11 more
wiley   +1 more source

OsMYB306‐OsRAV11 Regulates Resistance of Rice to Striped Stem Borer by Modulating Serotonin Biosynthesis

Plant Biotechnology Journal, Volume 24, Issue 8, Page 4951-4965, August 2026.
ABSTRACT Striped stem borer (SSB; Chilo suppressalis Walker) is one of the most destructive pests in rice production. Previous studies have demonstrated that SSB infestation induces transcription of OsT5H (tryptamine‐5‐hydroxylase) and biosynthesis of serotonin, a newly recognised phytohormone, and that disruption of serotonin biosynthesis ...
Jia‐Run Zhang, Long Wang, Yang‐Fan Chen, Xiao‐Hao Guo, Meng Jiang, Yuan‐Yuan Tan, Qing Wang, Qiu Qian, Angharad M. R. Gatehouse, Qing‐Yao Shu   +9 more
wiley   +1 more source