Results 71 to 80 of about 2,854 (189)

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, Volume 183, Issue 14, Page 4058-4071, July 2026.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling

Swiss Medical Weekly, 2015
Novel psychoactive substances are newly used designer drugs (“internet drugs”, “research chemicals”, “legal highs”) potentially posing similar health risks to classic illicit substances.
Matthias Liechti
doaj   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, Volume 183, Issue 14, Page 4006-4021, July 2026.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Designer drugs: aspectos analíticos e biológicos

Química Nova, 2012
In the recent years, analytical toxicologists have been facing difficulties in detecting designer drugs due to the chemical modifications on the existing structures and the speed in which they are released into the market, requiring the development and ...
Rachel Bulcão, Solange Cristina Garcia, Renata Pereira Limberger, Marília Baierle, Marcelo Dutra Arbo, Alice Aparecida da Matta Chasin, Flávia Valladão Thiesen, Rejane Tavares   +7 more
doaj   +1 more source

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt, Michael Farrell, Michael Doyle, Jack Stone, Chrianna Bharat, Matt Hickman, Marianne Martinello, Don Weatherburn, Kimberlie Dean, Joe Coyte, Christel Macdonald, Mary Ellen Harrod, Luke Grant, Gloria Larman, Peter Vickerman, Colette McGrath, Peter Thompson, Alison Churchill, Greg Dore, Thomas Santo Jr   +19 more
wiley   +1 more source

Effects of tryptamine on duckweed growth

Frontiers in Plant Science
Introduction Plant growth regulation involves complex biochemical and signaling pathways. Tryptamine (Try), a polyamine derived from tryptophan, has been implicated in plant growth and stress responses, yet its specific regulatory mechanisms have not been fully understood.
Qiqi Di, Wenqian Han, Yujie Han, Sizheng Liu, Yi Hu, Ziyang Qu, Yumeng Jiang, Weibo Sun, Ting Qiu, Lin Yang   +9 more
openaire   +3 more sources

Progressing Cross‐Sector Collaboration for People With Eating Disorders and Higher Weight: Priority Actions From an Expert Roundtable Using a Modified Nominal Group Technique

Medical Journal of Australia, Volume 224, Issue 7, July 2026.
ABSTRACT Introduction Eating disorders are more prevalent in people with higher weight than those with low weight. However, contention between the fields of obesity and eating disorders has prevented meaningful progress in research, prevention, identification and coordinated clinical services for people with co‐occurring conditions.
Hiba Jebeile, Leah Brennan, Tracy Burrows, Xochitl de la Piedad Garcia, Angelique F. Ralph, Supreet Saluja, Evan Atlantis, Sarah P. Garnett, Carmel J. Harrison, Eve T. House, Natalie B. Lister, Lisa Moran, Milan K. Piya, Elizabeth Rieger, Evelyn Smith, Phillipa Hay, Sarah Trobe   +16 more
wiley   +1 more source

Innovating Electrosynthesis From Metal Electrodeposition to Organic Chemistry: Deep Eutectic Solvents as Efficient and Sustainable Media

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
This review analyzes deep eutectic solvents (DESs) as efficient media for both organic and inorganic electrosynthesis. The improvements in terms of synthetic opportunities and sustainability are discussed, by exploring the multiple roles of DESs as solvents, electrolytes, and promoters, enabling effective and selective electrosynthesis under mild and ...
Cristiana Margarita, Stefano Nejrotti, Alejandro Leal‐Duaso, Marta Feroci, Alessandra Sanson, Claudia Barolo, Matteo Bonomo   +6 more
wiley   +1 more source

Enzymatic oxidation of substituted tryptamines catalysed by monoamine oxidase

Nukleonika, 2014
The enzymatic deamination of 5-fl uorotryptamine and 5-hydroxytryptamine, 5-HT, catalysed by enzyme monoamine oxidase A (MAO-A, EC 1.4.3.4) was investigated using the kinetic (KIE) and solvent (SIE) isotope effects methods.
Dragulska Sylwia, Kańska Marianna
doaj   +1 more source