Results 31 to 40 of about 3,690 (207)
Neuropsychiatric diseases such as depression, anxiety, and post-traumatic stress represent a substantial long-term challenge for the global health systems because of their rising prevalence, uncertain neuropathology, and lack of effective pharmacological
Erika Plazas, Nicoletta Faraone
doaj +1 more source
Synthesis of β-substituted tryptamines by regioselective ring opening of aziridines
Functionalized tryptamines are targets of interest for development as small molecule therapeutics. The ring opening of aziridines with indoles is a powerful method for tryptamine synthesis if site selectivity can be controlled.
Jeremy B. Morgan +5 more
core +2 more sources
Alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT), and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT) are three synthetic tryptamines with hallucinogenic properties that are widely abused worldwide.
Kaixi Li +7 more
doaj +1 more source
The methanol and ethanol solvates of 4-glutarato-N,N-diisopropyltryptamine
The solid-state structures of two solvated forms of 4-glutarato-N,N-diisopropyltryptamine were determined by single-crystal X-ray diffraction, namely, 5-[(3-{2-[bis(propan-2-yl)azaniumyl]ethyl}-1H-indol-4-yl)oxy]-5-oxopentanoate methanol monosolvate ...
Marilyn Naeem +4 more
doaj +1 more source
Analysis of tryptamines in whole blood by UHPLC-MS/MS [PDF]
Tryptaminer er en undergruppe av nye psykoaktive substanser (NPS) med økende forekomst i senere år. I tillegg kan en fornyet interesse for medisinsk bruk av tryptaminer føre til økt bruk i samfunnet.
Eidhammer, Monica Kvitrud
core
The solid-state structures of the salts of three psilacetin derivatives, namely, 4-acetoxy-N-ethyl-N-methyltryptammonium (4-AcO-MET) hydrofumarate {systematic name: [2-(4-acetyloxy-1H-indol-3-yl)ethyl](methyl)ethylazanium 3-carboxyprop-2-enoate ...
Duyen N. K. Pham +3 more
doaj +1 more source
Bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) fumarate: a new crystalline form of miprocin
The title compound, bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) (4-HO-MiPT) fumarate (systematic name: bis{[2-(4-hydroxy-1H-indol-3-yl)ethyl](methyl)propan-2-ylazanium} but-2-enedioate), 2C14H21N2O+·C4H2O42−, has a singly protonated tryptammonium ...
Andrew R. Chadeayne +3 more
doaj +1 more source
5-MeO-DALT: the freebase of N,N-diallyl-5-methoxytryptamine
The title compound {systematic name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-(prop-2-en-1-yl)prop-2-en-1-amine), C17H22N2O, has a single tryptamine molecule in the asymmetric unit.
Andrew R. Chadeayne +3 more
doaj +1 more source
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Synthesis of functionalized tryptamines by Brønsted acid catalysed cascade reactions [PDF]
An original synthetic protocol has been developed for the preparation of highly functionalized tryptamines from 2-hydroxycyclobutanone and secondary arylamines via a solvent-free Brønsted acid catalysed two-step reaction ...
MELIS, NICOLA +4 more
core +1 more source

