Results 31 to 40 of about 2,854 (189)

A systematic study of changes in monoamine neurotransmitters in the rat brain following acute administration of alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT) and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT)

open access: yesNeuroscience Research
Alpha-methyltryptamine (AMT), 5-methoxy-alpha-methyltryptamine (5-MeO-AMT), and 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DiPT) are three synthetic tryptamines with hallucinogenic properties that are widely abused worldwide.
Kaixi Li   +7 more
doaj   +1 more source

Bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) fumarate: a new crystalline form of miprocin

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
The title compound, bis(4-hydroxy-N-isopropyl-N-methyltryptammonium) (4-HO-MiPT) fumarate (systematic name: bis{[2-(4-hydroxy-1H-indol-3-yl)ethyl](methyl)propan-2-ylazanium} but-2-enedioate), 2C14H21N2O+·C4H2O42−, has a singly protonated tryptammonium ...
Andrew R. Chadeayne   +3 more
doaj   +1 more source

5-MeO-DALT: the freebase of N,N-diallyl-5-methoxytryptamine

open access: yesIUCrData, 2020
The title compound {systematic name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-(prop-2-en-1-yl)prop-2-en-1-amine), C17H22N2O, has a single tryptamine molecule in the asymmetric unit.
Andrew R. Chadeayne   +3 more
doaj   +1 more source

Organocatalytic asymmetric synthesis of bioactive hexahydropyrrolo[2,3-b]indole-containing tetrasubstituted allenes bearing multiple chiral elements

open access: yesTetrahedron Chem, 2022
An organocatalytic asymmetric construction of hexahydropyrrolo[2,3-b]indole-containing tetrasubstituted allene scaffolds bearing both axial chirality and central chirality has been established via a cascade 1,8-addition/dearomatization-cyclization ...
Jing-Yi Wang   +7 more
doaj   +1 more source

Exploring Endogenous Tryptamines: Overlooked Agents Against Fibrosis in Chronic Disease? A Narrative Review

open access: yesLivers
Long regarded as illicit substances with no clinical value, N-dimethylated tryptamines—such as N,N-dimethyltryptamine, 5-methoxy-N,N-dimethyltryptamine, and bufotenine—have been found to produce naturally in a wide variety of species, including humans ...
Hunter W. Korsmo
doaj   +1 more source

Quaternary tryptammonium salts: N,N-dimethyl-N-n-propyltryptammonium (DMPT) iodide and N-allyl-N,N-dimethyltryptammonium (DMALT) iodide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2020
The solid-state structures of two quaternary trytpammonium salts, namely, N,N-dimethyl-N-n-propyltryptammonium (DMPT) iodide [systematic name: 2-(1H-indol-3-yl)-N,N-dimethyl-N-propylazanium iodide], C15H23N2+·I−, and N-allyl-N,N-dimethyltryptammonium ...
Andrew R. Chadeayne   +3 more
doaj   +1 more source

Correlation of Tryptamine-Induced Convulsions in Rats with Brain Tryptamine Concentration

open access: yesExperimental Biology and Medicine, 1960
SummaryNormal rat brain tryptamine concentration was 0.032 ± 0.002 μg/g (mean ± S.E.M.). Oral administration of 0.72 mg/ kg of tranylcypromine (trans 2-phenylcyclopropylamine) or 25 mg/kg of iproniazid (1-isonicotinyl-2-isopropyl hydrazine) had no apparent effect upon normal rat brain tryptamine concentration. Sixty to 75 seconds after i.v.
H, GREEN, J L, SAWYER
openaire   +2 more sources

Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production

open access: yesFrontiers in Immunology, 2021
The liver is the central hub for processing and maintaining homeostatic levels of dietary nutrients especially essential amino acids such as tryptophan (Trp).
Soumya R. Mohapatra   +15 more
doaj   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

open access: yesAdvanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang   +17 more
wiley   +1 more source

N-Methyl-N-propyltryptamine (MPT)

open access: yesIUCrData, 2019
The title compound {systematic name: [2-(1H-indol-3-yl)ethyl](methyl)propylamine}, C14H20N2, has a single molecule in the asymmetric unit. The molecules in the unit cell are held together in infinite one-dimensional chains along [010] through N—H...N ...
Andrew R. Chadeayne   +2 more
doaj   +1 more source

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