Results 11 to 20 of about 3,690 (207)
Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signalling [PDF]
Swiss Medical Weekly, 2015 Novel psychoactive substances are newly used designer drugs (“internet drugs”, “research chemicals”, “legal highs”) potentially posing similar health risks to classic illicit substances.
Matthias Liechti
doaj +2 more sources
LiversLong regarded as illicit substances with no clinical value, N-dimethylated tryptamines—such as N,N-dimethyltryptamine, 5-methoxy-N,N-dimethyltryptamine, and bufotenine—have been found to produce naturally in a wide variety of species, including humans ...
Hunter W. Korsmo
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, 2022 An efficient synthesis of tryptamines is developed. Indole structures were constructed using 2-iodoaryl allenyl amines as electron acceptors and radical cyclization precursors. Radical–radical coupling of indolyl methyl radicals and azaallyl radicals led
Bo Wang (86769) +5 more
core +7 more sources
Effect of oral tryptamines on the gut microbiome of rats—a preliminary study [PDF]
PeerJBackground Psilocybin and related tryptamines have come into the spotlight in recent years as potential therapeutics for depression. Research on the mechanisms of these effects has historically focused on the direct effects of these drugs on neural ...
Mengyang Xu +4 more
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Trends in new psychoactive substance poisonings in the Netherlands: A 14-year retrospective analysis (2012-2025). [PDF]
AddictionAbstract Background and aims Data on the presence of new psychoactive substances (NPS) mainly originate from drug‐checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands.
Nugteren-van Lonkhuyzen JJ +5 more
europepmc +2 more sources
Recreational use, analysis and toxicity of tryptamines [PDF]
, 2015 The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
ROMOLO, Francesco Saverio +4 more
core +2 more sources
New Synthetic Technologies for the Construction of Heterocycles and Tryptamines
, 2016 New synthetic methods for the construction of novel heterocycles and tryptamines are described. Thus, N-Boc anilines (I) are sequentially converted to heterocycles II ((3-(2-aminophenyl)pyrrolidin-3-ol) derivatives), III (substituted 2-oxo-1,2 ...
Vincent É. Trépanier (2367796) +4 more
core +5 more sources
Gold-Catalyzed Synthesis of 2-Sulfenylspiroindolenines via Spirocyclizations
Molbank, 2018 2-Phenylsulfenyl-N-propargyl tryptamines have been prepared by electrophilic sulfuration of the corresponding tryptamines. These compounds undergo gold-catalyzed spirocyclizations to the corresponding 2-phenylthiospiroindolenines in good yields.
Valentin Magné +4 more
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The hydrochloride salt of 4-hydroxy-N,N-di-n-propyltryptamine (4-HO-DPT)
IUCrData, 2020 The title compound, 4-hydroxy-N,N-di-n-propyltryptammonium (4-HO-DPT) chloride {systematic name: N-[2-(4-hydroxy-1H-indol-3-yl)ethyl]-N-propylpropan-1-aminium chloride}, C16H25N2O+·Cl−, has a singly protonated tryptammonium cation and one chloride anion ...
Vamshikrishna Reddy Sammeta +4 more
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`Foxtrot' fumarate: a water-soluble salt of N,N-diallyl-5-methoxytryptamine (5-MeO-DALT)
Acta Crystallographica Section E: Crystallographic Communications, 2021 The title compound, bis(N,N-diallyl-5-methoxytryptammonium) (5-MeO-DALT) fumarate (systematic name: bis{N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- N-(prop-2-en-1-yl)prop-2-en-1-aminium} (E)-but-2-enedioate), 2C17H23N2O+·C4H2O42−, has a single tryptammonium ...
Duyen N. K. Pham +4 more
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