Results 1 to 10 of about 14,984 (246)
Modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms [PDF]
eLifeClassical psychedelics induce complex visual hallucinations in humans, generating percepts that are coherent at a low level, but which have surreal, dream-like qualities at a high level.
Colin Bredenberg +3 more
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The combination of exercise and psychedelics for the treatment of major depressive disorder [PDF]
Discover Mental HealthUpwards of 50% of people do not respond to the primary treatment modalities for major depressive disorder (MDD), which has led to increased attention and use of alternative methods, including exercise and psychedelics.
Nicholas Fabiano +7 more
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Pharmacological Reviews, 2016 Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter perception and mood and affect numerous cognitive processes. They are generally considered physiologically safe and do not lead to dependence or addiction. Their origin predates written history, and they were employed by early cultures in many sociocultural and ...
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Frontiers in Psychiatry, 2021 Clinical studies suggest the therapeutic potential of psychedelics, including ayahuasca, DMT, psilocybin, and LSD, in stress-related disorders. These substances induce cognitive, antidepressant, anxiolytic, and antiaddictive effects suggested to arise ...
Natasha L Mason, Kim P. C. Kuypers
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Self-medication with psychedelics: a scoping review and narrative synthesis of review-level evidence [PDF]
Exploratory Research in Clinical and Social PharmacyBackground: As public and scientific interest in psychedelics grows, unsupervised use for health purposes is increasing. In the U.S., past-year hallucinogen use nearly doubled from 2015 to 2023.
Shreya Shiju +2 more
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Best practices for first psychedelic experiences: harm reduction advice from the psychedelic community [PDF]
Harm Reduction JournalBackground The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This
Daniel J. Kruger +7 more
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Knowledge, perceptions, and use of psychedelics for mental health among autistic adults: An online survey. [PDF]
PLOS Mental HealthPsychedelics such as psilocybin, LSD, and MDMA have shown promise in treating mental health conditions (e.g., depression, post-traumatic stress disorder) among neurotypical individuals, i.e., typically developing individuals without a diagnosed ...
Sahba Afsharnia +5 more
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Virtual reality and psychedelics: new perspectives and new possibilities in the treatment of alcohol use disorder [PDF]
Frontiers in PsychiatryPsychedelic-assisted therapy is a remarkably promising treatment for substance use disorders and for alcohol use disorder (AUD) in particular. Research supporting psychedelics as a safe and effective pharmacotherapy for AUD and its comorbid psychiatric ...
Scott Matthews +11 more
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Current Biology, 2022 Psychedelics are compounds that alter consciousness by acting on serotonin receptors in the brain. The term 'psychedelic', from the Greek for mind manifesting, refers to the drugs' subjective effects and was first proposed by Humphry Osmond in 1956. Other terms have been used to emphasize different aspects of the psychological experiences produced by ...
Benjamin, Kelmendi +3 more
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Frontiers in Pharmacology, 2023 Introduction:N-2-methoxy-benzylated (“NBOMe”) analogues of phenethylamine are a group of new psychoactive substances (NPS) with reported strong psychedelic effects in sub-milligram doses linked to a number of severe intoxications, including fatal ones ...
Kateřina Syrová +20 more
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