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Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics [PDF]
Frontiers in Psychiatry, 2021 Clinical studies suggest the therapeutic potential of psychedelics, including ayahuasca, DMT, psilocybin, and LSD, in stress-related disorders. These substances induce cognitive, antidepressant, anxiolytic, and antiaddictive effects suggested to arise ...
N L Mason, Kim P C Kuypers
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Psychedelics and Psychedelic-Assisted Psychotherapy
American Journal of Psychiatry, 2020 The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders.Searches of PubMed and PsycINFO via Ovid were conducted for articles in English, in peer-reviewed journals, reporting on "psilocybin," "lysergic acid diethylamide," "LSD," "ayahuasca," "3,4 ...
Collin Reiff, Carolyn Rodríguez
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Pharmacological Reviews, 2016 Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter perception and mood and affect numerous cognitive processes. They are generally considered physiologically safe and do not lead to dependence or addiction. Their origin predates written history, and they were employed by early cultures in many sociocultural and ...
David E. Nichols, Nichols, David E.
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Current Biology, 2022 Psychedelics are compounds that alter consciousness by acting on serotonin receptors in the brain. The term 'psychedelic', from the Greek for mind manifesting, refers to the drugs' subjective effects and was first proposed by Humphry Osmond in 1956. Other terms have been used to emphasize different aspects of the psychological experiences produced by ...
Benjamin, Kelmendi +3 more
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Frontiers in Pharmacology, 2023 Introduction:N-2-methoxy-benzylated (“NBOMe”) analogues of phenethylamine are a group of new psychoactive substances (NPS) with reported strong psychedelic effects in sub-milligram doses linked to a number of severe intoxications, including fatal ones ...
Kateřina Syrová +20 more
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Medical student attitudes and perceptions of psychedelic-assisted therapies
Frontiers in Psychiatry, 2023 IntroductionAlthough certain psychedelic agents may soon gain federal approval for use in treating specific psychiatric conditions, the utilization of such therapies in clinical practice will depend largely on the attitudes of healthcare providers ...
Irene Li +5 more
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Effects of classic psychedelic drugs on turbulent signatures in brain dynamics
Network Neuroscience, 2022 Psychedelic drugs show promise as safe and effective treatments for neuropsychiatric disorders, yet their mechanisms of action are not fully understood.
Josephine Cruzat +12 more
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The association between naturalistic use of psychedelics and co-occurring substance use disorders
Frontiers in Psychiatry, 2023 ObjectiveClassic psychedelics (LSD, psilocybin, and peyote/mescaline) have been used to support addiction treatment in a variety of contexts ranging from ceremonial use to clinical trials.
Jonina Rabinowitz +6 more
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Frontiers in Psychiatry, 2023 IntroductionPsychedelic-assisted therapy with psilocybin has shown promise in Phase 2 trials for alcohol use disorder (AUD). Set and setting, particularly factors facilitating a connection with nature, may positively influence the psychedelic experience ...
Keith G. Heinzerling +11 more
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Psychedelics and Personality [PDF]
ACS Chemical Neuroscience, 2018 In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders.
Marc, Aixalà +3 more
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