Results 31 to 40 of about 14,984 (246)

Reaction of N,N-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions. [PDF]

open access: yes, 2018
A large number of clinically used drugs and experimental pharmaceuticals possess the N,N-dimethyltryptamine (DMT) structural core. Previous reports have described the reaction of this motif with dichloromethane (DCM), a common laboratory solvent used ...
Dunlap, Lee E, Olson, David E
core   +3 more sources

Psychedelic Cognition—The Unreached Frontier of Psychedelic Science

open access: yesFrontiers in Neuroscience, 2022
Psychedelic compounds hold the promise of changing the face of neuroscience and psychiatry as we know it. There have been numerous proposals to use them to treat a range of neuropsychiatric conditions such as depression, anxiety, addiction and PTSD; and trials to date have delivered positive results in favor of the novel therapeutics.
openaire   +5 more sources

Psychedelics and Personality [PDF]

open access: yesACS Chemical Neuroscience, 2018
In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders.
Marc, Aixalà   +3 more
openaire   +2 more sources

Psychedelic Experiences During the Early COVID-19 Pandemic: Findings From an International Online Survey

open access: yesFrontiers in Psychiatry, 2021
Introduction: The current corona virus disease (COVID-19) pandemic has caused a serious global health crisis that has affected large parts of the public and private life worldwide, including the use of psychoactive substances.
Ricarda Evens   +19 more
doaj   +1 more source

Slouching towards engagement: interactions between people using psychedelics naturalistically and their healthcare providers

open access: yesFrontiers in Psychiatry, 2023
IntroductionThere is substantial public interest in psychedelics as potential treatments for psychiatric conditions. However, most psychedelics are criminalized under federal law in the USA, so it is unclear whether use occurs with clinical support.
Kevin F. Boehnke   +17 more
doaj   +1 more source

Investigating Emotional Reactivity in Experienced Users of Psychedelics: A Cross-Sectional fMRI Study. [PDF]

open access: yesHum Brain Mapp
This cross‐sectional fMRI study compared experienced psychedelic users and matched nonusers on behavioral and neural responses to emotional facial expressions. Findings reveal neurofunctional differences between groups in emotional reactivity, highlighting both similarities and important distinctions in the long‐term effects of naturalistic versus ...
Orłowski P, Domagalik A, Bola M.
europepmc   +2 more sources

Alterations in brain network connectivity and subjective experience induced by psychedelics: a scoping review

open access: yesFrontiers in Psychiatry
Intense interest surrounds current research on psychedelics, particularly regarding their potential in treating mental health disorders. Various studies suggest a link between the subjective effects produced by psychedelics and their therapeutic efficacy.
Zijia Yu   +20 more
doaj   +1 more source

Psychedelics: A new era of treatment?

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +1 more source

Psilocybin during the postpartum period induces long-lasting adverse effects in both mothers and offspring

open access: yesNature Communications
Psilocybin increases social connectedness and has strong clinical transdiagnostic efficacy for mental illness, making it a candidate treatment to reduce maternal disconnect, anxiety, and blunted affect seen in peripartum mood disorders.
Cassandra J. Hatzipantelis   +15 more
doaj   +1 more source

Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment

open access: yesFrontiers in Pharmacology
IntroductionCanine osteoarthritis (OA) is a prevalent disease characterized by progressive joint degeneration, pain, and impaired mobility. In older dogs, OA affects approximately 80% of the population.
Neide Maria Griebeler   +12 more
doaj   +1 more source

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