Results 1 to 10 of about 12,958 (242)
Unifying Theories of Psychedelic Drug Effects
Frontiers in Pharmacology, 2018 How do psychedelic drugs produce their characteristic range of acute effects in perception, emotion, cognition, and sense of self? How do these effects relate to the clinical efficacy of psychedelic-assisted therapies?
Link R. Swanson +2 more
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Major life changes following psychedelic use: A retrospective survey among people using psychedelics naturalistically [PDF]
Scientific ReportsPsychedelic drugs show promise in facilitating a variety of long-term psychological changes, but they may also lead to unexpected major life changes that have not been captured by measures typically used in clinical trials.
Jacob S. Aday +9 more
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Case analysis of long-term negative psychological responses to psychedelics
Scientific Reports, 2023 Recent controversies have arisen regarding claims of uncritical positive regard and hype surrounding psychedelic drugs and their therapeutic potential. Criticisms have included that study designs and reporting styles bias positive over negative outcomes.
Rebecka Bremler +4 more
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Effects of psilocybin versus escitalopram on rumination and thought suppression in depression
BJPsych Open, 2022 Background Major depressive disorder is often associated with maladaptive coping strategies, including rumination and thought suppression. Aims To assess the comparative effect of the selective serotonin reuptake inhibitor escitalopram, and the ...
Tommaso Barba +8 more
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Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing
Scientific Reports, 2021 Psychedelic microdosing describes the ingestion of near-threshold perceptible doses of classic psychedelic substances. Anecdotal reports and observational studies suggest that microdosing may promote positive mood and well-being, but recent placebo ...
L. S. Kaertner +9 more
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Scientific Reports, 2023 In medical trials, ‘blinding’ ensures the equal distribution of expectancy effects between treatment arms in theory; however, blinding often fails in practice.
Balázs Szigeti +3 more
doaj +1 more source
Frontiers in Psychiatry, 2022 Survey-based studies suggest naturalistic psychedelic use provides mental health benefits similar to those observed in clinical trials. The current study sought to confirm these findings in a large group of psychedelic users and to conduct a novel ...
Charles L. Raison +4 more
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Scientific Reports, 2023 Psilocybin and lysergic acid diethylamide (LSD) experiences can range from very positive to highly challenging (e.g., fear, grief, and paranoia). These challenging experiences contribute to hesitancy toward psychedelic-assisted psychotherapy among health
Richard J. Zeifman +7 more
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Frontiers in Psychology, 2023 The growing interest in and prevalence of the use of psychedelics, as well as the potential benefits and negative consequences associated with psychedelic experiences, create a need for mental health specialists to be able to provide adequate and ...
Jakub Greń +8 more
doaj +1 more source
Self-blinding citizen science to explore psychedelic microdosing
eLife, 2021 Microdosing is the practice of regularly using low doses of psychedelic drugs. Anecdotal reports suggest that microdosing enhances well-being and cognition; however, such accounts are potentially biased by the placebo effect.
Balázs Szigeti +7 more
doaj +1 more source