Results 21 to 30 of about 25,012 (219)

Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness

open access: yesFrontiers in Pharmacology, 2021
Background: Recent years have seen a resurgence of research on the potential of psychedelic substances to treat addictive and mood disorders. Historically and contemporarily, psychedelic studies have emphasized the importance of contextual elements ('set
H. Kettner   +7 more
doaj   +1 more source

Psychedelics alter metaphysical beliefs

open access: yesScientific Reports, 2021
Can the use of psychedelic drugs induce lasting changes in metaphysical beliefs? While it is popularly believed that they can, this question has never been formally tested.
Christopher Timmermann   +5 more
doaj   +1 more source

CE: Psychedelic-Assisted Therapy [PDF]

open access: yes, 2021
Psychedelics are a class of psychoactive substances that were studied extensively between 1943 and 1970 as potential therapies for treating a host of mental health disorders, including addiction. Despite promising early results, U.S. psychedelic research
Dorsen, Caroline G   +7 more
core   +1 more source

Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

open access: yesFrontiers in Neuroscience, 2023
IntroductionPsilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT2A receptors, it has high binding affinity also to 5 ...
Filip Tylš   +20 more
doaj   +1 more source

What Conceptual Metaphors Appear in Texts on Psychedelics and Medicine? Corpus-Based Cognitive Study

open access: yesRespectus Philologicus, 2022
This paper aims to present conceptual metaphors employed to discuss psychedelics in texts published online by organizations popularizing knowledge about psychedelic substances. The foundation of this investigation comprises Cognitive Grammar, Conceptual
Milena Bryła
doaj   +1 more source

Interest in receiving psychedelic-assisted therapy among marginalized women: Implications and findings from a community-based study in Canada

open access: yesDrug and Alcohol Dependence Reports, 2022
Background: Psychedelic-assisted therapies are receiving mounting attention for their therapeutic potential. However, little is known about interest among women who experience elevated risk of mental health and substance use disorders.
Elena Argento   +6 more
doaj   +1 more source

Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential

open access: yesNature Communications, 2023
Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5-HT2A-Gq/11 and β-arrestin2 transducers, making their respective roles ...
Jason Wallach   +18 more
doaj   +1 more source

Relational Processes in Ayahuasca Groups of Palestinians and Israelis

open access: yesFrontiers in Pharmacology, 2021
Psychedelics are used in many group contexts. However, most phenomenological research on psychedelics is focused on personal experiences. This paper presents a phenomenological investigation centered on intersubjective and intercultural relational ...
Leor Roseman   +8 more
doaj   +1 more source

Mindset over molecule: comparing self-transcendent and mystical experiences across recreational psilocybin, MDMA, and cannabis use

open access: yesBMC Psychology
Background Self-transcendent and mystical experiences may be key mechanisms underlying psychedelics’ therapeutic effects, yet how these experiences differ across substances remains unclear.
Christina Chwyl   +3 more
doaj   +1 more source

An ETH‐LAD trip with unfavourable consequences: A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Numerous analogues of the psychedelic and internationally controlled hallucinogen LSD have been described; however, only a limited number have been systematically investigated. This report presents the first case with an analytically confirmed ingestion of ETH‐LAD (6‐ethyl‐6‐nor‐lysergic acid diethylamide), the N‐ethyl derivative of LSD.
Johannes Nadler   +6 more
wiley   +1 more source

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