Results 211 to 220 of about 429,874 (275)
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Recent Progress in Biological Activities of Indole and Indole Alkaloids
Mini-Reviews in Medicinal Chemistry, 2017Dr. Thokchom Prasanta Singh +1 more
exaly +2 more sources
Indole alkaloids, synthetic dimers and hybrids with potential in vivo anticancer activity.
Current Topics in Medicinal Chemistry, 2020Indole, a heterocyclic organic compound, is one of the most promising heterocycles found in natural and synthetic sources since its derivatives possess fascinating structural diversity and various therapeutic properties.
Feng Song +7 more
semanticscholar +1 more source
The antimalarial activity of indole alkaloids and hybrids
Archiv der Pharmazie, 2020Malaria, caused by the genus Plasmodium, remains a global public health concern. It is estimated by the World Health Organization that over 40% of the world's population lives in areas at risk for malarial transmission, and around half a million people ...
Jue-Ying Li +6 more
semanticscholar +1 more source
Cytotoxicity of Modified Indole Alkaloids
Journal of Pharmaceutical Sciences, 1979Indole alkaloids of the iboga series were structurally modified by incorporation of a 3,4-dimethoxybenzyl or -benzoyl unit so that they contained the N-O-O triangle required for antileukemic activity according to the triangulation hypothesis. The cytotoxicities of the modified alkaloids in the in vitro P-388 system were not significantly increased over
D G, Kingston, S M, Sami
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Indole Prenylation in Alkaloid Synthesis
2011Important biologically active indole alkaloids are decorated with prenyl (3,3-dimethylallyl) and tert-prenyl (1,1-dimethylallyl) groups. Covering the literature until the end of 2010, this review article comprehensively summarises and discusses the currently available technologies of prenylation and tert-prenylation of indoles, which have been applied ...
Thomas, Lindel +2 more
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Phytochemistry, 2019
Qing Dai (Naturalis Indigo) is a traditional Chinese medicine (TCM) used as a topical agent in moderate psoriasis, targeting interleukin-17 (IL-17). In this study, it was prepared from the aerial parts of Strobilanthes cusia.
Chia-Lin Lee +8 more
semanticscholar +1 more source
Qing Dai (Naturalis Indigo) is a traditional Chinese medicine (TCM) used as a topical agent in moderate psoriasis, targeting interleukin-17 (IL-17). In this study, it was prepared from the aerial parts of Strobilanthes cusia.
Chia-Lin Lee +8 more
semanticscholar +1 more source
Moschamine-Related Indole Alkaloids
2018Moschamine-related alkaloids originate mainly from feruloylserotonin by cyclization or dimerization. This review provides a comprehensive overview on the achievements in the field of moschamine-related alkaloids. In the isolation part, a detailed structural characterization of moschamine-related alkaloids is followed by their spectral data. Besides the
Chengfeng, Xia, Xiaogang, Tong
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Natural indole‐containing alkaloids and their antibacterial activities
Archiv der Pharmazie, 2020As the growth in resistance to bacterial infection treatments poses a grave threat to global health in the 21st century, there is a constant need to explore novel antibacterial agents that have the ability to overcome drug resistance.
Yang Liu +5 more
semanticscholar +1 more source
Transformation of quinine into the indole alkaloids—I
Tetrahedron, 1969Abstract The configurations at C4′ of normal and allo hexahydroquinine (IIIa and IIIb) obtained by catalytic hydrogenation of dibydroquinine (II) were proven to be α and β, respectively.
Y.K. Sawa, H. Matsumura
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Bioorganic chemistry (Print), 2019
Active plant metabolites have been used as prototype drugs. In this context, Tabernaemontana catharinensis (Apocynaceae) has been highlighted because of the presence of active indole alkaloids.
P. F. Rosales +7 more
semanticscholar +1 more source
Active plant metabolites have been used as prototype drugs. In this context, Tabernaemontana catharinensis (Apocynaceae) has been highlighted because of the presence of active indole alkaloids.
P. F. Rosales +7 more
semanticscholar +1 more source