Results 121 to 130 of about 3,209 (136)

Indoleamine 2,3-dioxygenase 1 alters the proportions of B cell subpopulations in the microenvironment of acute myeloid leukemia. [PDF]

Mol Biomed
Yao Y, Liu YY, Li JF, Chen YS, Shi L, Shen Y, Yang LL, Yang Q.   +7 more
europepmc   +1 more source

Enzymatic and mechanistic studies into Tryptophan 2,3-Dioxygenase [PDF]

, 2009
Thackray, Sarah J.
core  

Immunohistochemical Profiling of IDO1 and IL4I1 in Head and Neck Squamous Cell Carcinoma: Interplay for Metabolic Reprogramming? [PDF]

Int J Mol Sci
Schmidl B, Lauterbach M, Stögbauer F, Mogler C, Ribbat-Idel J, Perner S, Wollenberg B.   +6 more
europepmc   +1 more source

Kynurenine Pathway after Kidney Transplantation: Friend or Foe? [PDF]

Int J Mol Sci
Zakrocka I, Urbańska EM, Załuska W, Kronbichler A.   +3 more
europepmc   +1 more source

Impact of Indoleamine 2,3-Dioxygenase Enzyme Activity in Neuroendocrine Tumors.

Neuroendocrinology
Mancini C, Pecora G, Salerno G, Lionetto L, De Bernardini D, Costanzi G, Gabrielli S, Veroli D, Visco V, Simmaco M, Zamponi V, Mazzilli R, Faggiano A.   +12 more
europepmc   +1 more source

Heme-based dioxygenases: Structure, function and dynamics. [PDF]

J Inorg Biochem
Geeraerts Z, Ishigami I, Gao Y, Yeh SR.
europepmc   +1 more source

Elucidating ligand interactions and small-molecule activation in the pyrrolnitrin biosynthetic enzyme PrnB. [PDF]

J Biol Chem
Li B, Usai R, Campbell J, Wang Y.
europepmc   +1 more source

Enzymatic Oxidation of Tryptophan and Its Analogues by Heme-Containing Dioxygenases [PDF]

Lubis, Ali B
core  

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Homology Modeling of Human Indoleamine-Pyrrole 2,3-Dioxygenase-2 (hIDO2) and Virtual Screening Approaches to Identify Novel, Potent, and Selective HIDO2 Inhibitors

Palestinian Medical and Pharmaceutical Journal, 2023
Indoleamine 2,3-dioxygenase 2 (IDO2) is a newly discovered target proposed to be a promising therapeutic modulator of various peripheral and central pathological states such as autoimmune disorders and immune escape diseases like cancer. The lack of potent hIDO2 inhibitors presents a high demand for discovering novel hIDO2 inhibition strategies to ex ...
Şüküroğlu, Murat, Qaoud, Mohammed
openaire   +2 more sources

Enhancement of dendritic cell-tumor fusion vaccine potency by indoleamine-pyrrole 2,3-dioxygenase inhibitor, 1-MT

Journal of Cancer Research and Clinical Oncology, 2007
Dendritic cell (DC)-based cancer vaccines are currently being evaluated as novel anti-tumor vaccination strategies, but in some cases, they are demonstrated to have poor clinical efficacies than anticipated. A potential reason is immune tolerance due to the immunosuppressive enzyme, indoleamine-pyrrole 2,3-dioxygenase (IDO).
Xueling, Ou, Shaohui, Cai, Peng, Liu, Jun, Zeng, Yuwen, He, Xinyao, Wu, Jun, Du   +6 more
openaire   +2 more sources