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Abstract 3847: Creating the tumor microenvironment for effective immunotherapy: Antitumor activity of intratumoral IMO-2125, a TLR9 agonist is further enhanced by inhibition of indoleamine-pyrrole 2,3-dioxygenase (IDO)

Cancer Research, 2016
Abstract In recent years, understanding of tumor immunology has led to significant advances in cancer immunotherapy. New approaches include selective blockade of checkpoints, harnessing tumor infiltrating lymphocytes (TILs) and use of intratumoral oncolytic viruses.
Daqing Wang   +5 more
openaire   +1 more source

Indoleamine-pyrrole 2,3-dioxygenase might be a prognostic biomarker for patients with renal cell carcinoma.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014
To explore the role of indoleamine-pyrrole 2,3-dioxygenase (IDO), an immunomodulatory enzyme, in renal cell carcinoma (RCC).A total of 40 patients diagnosed as RCC in the Second Xiangya Hospital were included in this study. All patients received nephrectomy. The histopathological features of samples were assessed semi-quantitatively.
Fang, Yuan   +3 more
openaire   +1 more source

Indoleamine-pyrrole 2,3-dioxygenase

1994
Dietmar Schomburg, Dörte Stephan
openaire   +1 more source

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