Results 171 to 180 of about 46,494 (229)
Some of the next articles are maybe not open access.
Indomethacin and prostaglandins
European Journal of Pharmacology, 1972Abstract The effects of indomethacin on inflammation mediators histamine, 5-hydroxytryptamine, bradykinin and prostaglandin E 2 have been studied. Indomethacin, 10–160 ωg/ml, exhibits an inhibitory effect on the contractions induced by each one of the studied mediators on isolated rat uterus and guinea pig ileum.
F Capasso
exaly +3 more sources
Pharmacokinetics of indomethacin
Clinical Pharmacology & Therapeutics, 1975Plasma concentrations of indomethacin have been studied in 5 healthy volunteers after single and multiple doses (25 mg intravenously [iv], 25, 50, and 100 mg orally, 100 mg rectally, and 25 mg three times daily [tid]. In 8 other normal subjects and in 5 patients a 50‐mg oral dose of indomethacin was given and the indomethacin concentration was followed
G, Alván +4 more
openaire +2 more sources
Journal of Toxicology: Clinical Toxicology, 1986
Two cases of indomethacin poisoning with supporting analytical data are described and the literature, which is limited to two reports, is reviewed. In overdose, indomethacin may produce the following non-life threatening symptoms: nausea, vomiting, abdominal pain, anorexia, drowsiness, headache, tinnitus, restlessness and agitation.
T M, Sheehan, D A, Boldy, J A, Vale
openaire +2 more sources
Two cases of indomethacin poisoning with supporting analytical data are described and the literature, which is limited to two reports, is reviewed. In overdose, indomethacin may produce the following non-life threatening symptoms: nausea, vomiting, abdominal pain, anorexia, drowsiness, headache, tinnitus, restlessness and agitation.
T M, Sheehan, D A, Boldy, J A, Vale
openaire +2 more sources
Archives of Dermatology, 1966
Twelve psoriatics have been observed in a controlled study with indomethacin, a nonsteroidal anti-inflammatory agent, as the test drug. No greater subjective or objective benefit was noted from indomethacin than from the placebo.
openaire +2 more sources
Twelve psoriatics have been observed in a controlled study with indomethacin, a nonsteroidal anti-inflammatory agent, as the test drug. No greater subjective or objective benefit was noted from indomethacin than from the placebo.
openaire +2 more sources
Mechanism of Action of Indomethacin in Indomethacin-Responsive Headaches
Current Pain and Headache Reports, 2013Indomethacin, as a member of the non-steroidal anti-inflammatory drug class, plays a special role in the treatment of headaches. By definition, it is completely efficacious in the treatment of the primary headache disorders paroxysmal hemicrania and hemicrania continua.
Oliver, Summ, Stefan, Evers
openaire +2 more sources
Premature labor and indomethacin
Prostaglandins, 1975Women in the 29th - 32nd week of gestation were admitted to hospital following the onset of premature labor contractions. After treatment with bed rest and beta-stimulating drugs, those patients with persistent uterine contractions were treated with oral indomethacin (25 mg every 6 hours for 5 days).
N, Wigvist, V, Lundström, K, Gréen
openaire +2 more sources
Drug Development and Industrial Pharmacy, 1994
AbstractThe prepared film-coated directly-compressed indo-methacin, indomethacin sodium and indomethacin meglumine tablets, plain indomethacin in hard gelatin capsule and the commercial product “Indocid” capsules, were subjected to bioavailability testing in six healthy volunteers. Each treatment was given as single oral dose of 50 mg.
Hamed El-shattawy +4 more
openaire +1 more source
AbstractThe prepared film-coated directly-compressed indo-methacin, indomethacin sodium and indomethacin meglumine tablets, plain indomethacin in hard gelatin capsule and the commercial product “Indocid” capsules, were subjected to bioavailability testing in six healthy volunteers. Each treatment was given as single oral dose of 50 mg.
Hamed El-shattawy +4 more
openaire +1 more source
Pharmacokinetic overview of indomethacin and sustained-release indomethacin
The American Journal of Medicine, 1985Indomethacin has a moderately short half-life, usually requiring dosing twice a day or three times a day. A more convenient once or twice daily regimen is made possible with a sustained-release formulation. Following multiple-dose administration of either sustained-release indomethacin (Indocin SR) or conventional indomethacin, drug accumulation is low.
openaire +2 more sources
Drug and Therapeutics Bulletin, 1965
Indomethacin (Indocid - MSD) is described as a ‘new, non-steroid anti-inflammatory agent with analgesic and antipyretic properties’. It has been supplied to hospitals only since November 1964, but will soon be available for prescription in general practice.
openaire +1 more source
Indomethacin (Indocid - MSD) is described as a ‘new, non-steroid anti-inflammatory agent with analgesic and antipyretic properties’. It has been supplied to hospitals only since November 1964, but will soon be available for prescription in general practice.
openaire +1 more source