Results 101 to 110 of about 8,033,780 (308)
Magnetohyperthermia for treatment of gliomas: experimental and clinical studies [PDF]
Einstein (São Paulo), 2010 Gliomas comprise a group of heterogeneous primary tumors of thecentral nervous system that originate from glial cells. Malignantgliomas account for the majority of primary malignant CNS tumorsand are associated with high morbidity and mortality ...
André César da Silva +7 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Induced technical change in agricultural development in Saudi Arabia
, 1994 The rapid rate of growth in Saudi agricultural development was a result of technology changes. Thus, three alternative hypotheses are proposed in this paper to explain the induced technical change in production growth.
Al-Kahtani, Safer H.
core
, 2013 The purpose of this pre-specified analysis of the PROlonging Dual antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY (PRODIGY) was to assess device-specific outcomes relative to different duration of dual antiplatelet therapy ...
TEBALDI, Matteo +6 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Geophysical Research Letters, 2018 Induced seismicity models that do not account for the effects of flow boundary conditions and uncertainty in initial stresses on the seismicity rate fail to predict the seismicity observed in real‐world injection sites.
S. M. Hosseini +3 more
doaj +1 more source
Induced terminations of pregnancy: reporting states, 1979 [PDF]
Numbers of induced abortions and induced abortion ratios increased between 1978 and 1979 for the multi- State area reporting this information to the National Center for Health Statistics.
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source