Results 81 to 90 of about 8,336,024 (249)

Comparison of Oral Misoprostol Solution and Cervical Balloon Placement for Labor Induction in Full-Term Pregnant Women With Unfavorable Cervical Conditions

Clinical and Experimental Obstetrics & Gynecology
Background: Labor induction in full-term pregnancies with unfavorable cervical conditions requires safe and effective methods. Oral misoprostol solution and cervical balloon placement are commonly used, but comparative evidence remains
Siting Lv, Lijuan Ding, Na Xu, Ni Wang, Chen Chen   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

An audit of delivery plans for babies with antenatal urinary tract abnormalities: the mothers’ perspective

Journal of Perinatal Medicine
There is little evidence guiding the delivery of babies who are antenatally detected to have antenatal urinary tract abnormalities (AN-UTA), and some clinicians would deliver early purely because of AN-UTA.
Green Patrick, Ndzi Agnes, Carey Giles, Adefolaju Anthonia, Agarwal Umber, Corbett Harriet J.   +5 more
doaj   +1 more source

Experimental Study on Water Injection Removal of Ammonium Chloride Particles to Enhance Hydrotreatment Air Cooler Reliability

Fuels
Hydrotreatment is vital for producing high-quality liquid fuels in petroleum refining and its air coolers are critical components prone to severe corrosion under high-temperature and high-pressure conditions.
Xiaofei Liu, Xin Chen, Zhengwei Zhang, Huayu Wen, Dongbo Chen, Haoyu Yin, Haozhe Jin, Chao Wang, Lite Zhang   +8 more
doaj   +1 more source

Bid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effects [PDF]

, 2008
Background: The BH3-only protein Bid is an important component of death receptor-mediated caspase activation. Bid is cleaved by caspase-8 or -10 into t-Bid, which translocates to mitochondria and triggers the release of caspase-activating factors.
Caoimhin G Concannon, Anguissola, Sergio, Barbara Köhler, Jochen H M Prehn, Markus Rehm (7899308), Kögel, Donat, Barbara Köhler (60110), Caoimhín G. Concannon (7953038), Donat Kögel, Sergio Anguissola, Prehn, Jochen H. M., Donat Kögel (60113), Köhler, Barbara, Rehm, Markus, Sergio Anguissola (60111), Jochen Prehn (7895672), Concannon, Caoimhin G., Markus Rehm   +17 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Induced technical change in agricultural development in Saudi Arabia

, 1994
The rapid rate of growth in Saudi agricultural development was a result of technology changes. Thus, three alternative hypotheses are proposed in this paper to explain the induced technical change in production growth.
Al-Kahtani, Safer H.
core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source