Results 71 to 80 of about 8,336,024 (249)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

caslu85/Induced-Gap-Closing-Shared: Induced-Gap-Closing-Shared

open access: yes, 2021
Repository release to share data for manuscript 'Closing of the Induced Gap in a Hybrid Superconductor-Semiconductor ...
caslu85
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Benefits of three consecutive sputum inductions using nebulized racemic salbutamol versus hypertonic saline in smear-negative or sputum-scarce pulmonary tuberculosis patients: a prospective randomized, double-blind study

open access: yesMicrobiology Spectrum
Although, sputum induction (SI) with hypertonic saline increases the diagnostic yield for suspected pulmonary tuberculosis (PTB) in patients with smear-negative microscopy, but, it carries adverse effects (AEs), particularly bronchospasm.
Warangkana Keeratichananont   +3 more
doaj   +1 more source

Influência da percepção dos profissionais quanto ao aborto provocado na atenção à saúde da mulher Perception influence of professionals regarding unsafe in attention to women's health

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2012
OBJETIVO: Identificar o conhecimento e a percepção dos profissionais da saúde em relação à legislação brasileira sobre o aborto provocado. MÉTODOS: Envelopes selados não identificados contendo os questionários foram enviados a todos os profissionais (n ...
Gláucia Rosana Guerra Benute   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Potential mediating role of self-concealment in the relationship between family resilience and stigma among women who have had induced abortions: a cross-sectional study

open access: yesFrontiers in Public Health
ObjectivesTo explore the factors associated with stigma among women undergoing induced abortion in China and to investigate whether self-concealment plays a potential mediating role between family resilience and stigma.MethodsThis was a cross-sectional ...
Tingting Ruan   +3 more
doaj   +1 more source

akilnarayan/induced-distributions: Initial beta release

open access: yes, 2017
<p>Initial release of induced distribution code:</p> <ul> <li>evaluation of induced distributions (Jacobi, half-line Freud, Freud)</li> <li>evaluation of inverse induced distributions</li> <li>random ...
akilnarayan
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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