Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Bone wax spacers increase induced membrane thickness and promote osteogenesis more than polymethylmethacrylate spacers in the masquelet technique. [PDF]
Nakatani T+8 more
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Radiation-induced injury and the gut microbiota: insights from a microbial perspective. [PDF]
Wang Q, Xu G, Yan O, Wang S, Wang X.
europepmc +1 more source
FURTHER STUDIES ON THE LIPOLYTIC SYSTEM INDUCED IN PLASMA BY HEPARIN INJECTION [PDF]
D. S. Robinson
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This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Delayed Chlorosis in Arabidopsis Ecotype Dijon-G During Bacterial Infection and Dark-Induced Senescence. [PDF]
Lee YH+4 more
europepmc +1 more source
THE RELATION OF THE VITAMINS TO THE REACTION INDUCED BY COAL TAR IN THE TISSUES OF ANIMALS [PDF]
Louis H. Jorstad
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Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Growth-induced percolation on complex networks. [PDF]
Sun H, Chen S, Xie J, Hu Y.
europepmc +1 more source