Results 201 to 210 of about 6,601,283 (299)

<i>Propionibacterium freudenreichii</i> MJ2 Improves Dexamethasone-Induced Muscle Atrophy in Rats by Increasing Muscle Mass and Muscle Fiber Area. [PDF]

J Microbiol Biotechnol
Kim SH, Woo HE, An M, Lim YH.
europepmc   +1 more source

Zingerone (4-(4-hydroxy-3-methylphenyl) butan-2-one) protects against alloxan-induced diabetes via alleviation of oxidative stress and inflammation: Probable role of NF-kB activation

, 2018
Sheikh Bilal Ahmad, Muneeb U. Rehman, Insha Amin, M. R. Mir, Sheikh Bilal Ahmad, Adil Farooq, Showkeen Muzamil Bashir, Ishraq Hussain, Mubashir Hussain Masoodi, Bilques Fatima   +9 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Ionizing radiation: molecular mechanisms, biological effects, and therapeutic targets. [PDF]

Mol Biomed
Wei W, Ren Y, Lan J, Yi J, Wang M, Zhang Y, Wang S, Xu Y, Han G, Fu Y, You L, Xue J, Jin S, Li J.   +13 more
europepmc   +1 more source

Protective effects of cyanidin‐3‐O‐glucoside on UVB‐induced chronic skin photodamage in mice via alleviating oxidative damage and anti‐inflammation

, 2020
Ziyao Peng, Xiaolong Hu, Xusheng Li, Xinwei Jiang, Liehua Deng, Yunfeng Hu, Weibin Bai   +6 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Pharmacogenomics of Thiopurine Drugs: A Bench-To-Bedside Success Story in Thailand. [PDF]

Clin Transl Sci
Biswas M, John S, Murad MA, Sukasem C.
europepmc   +1 more source

Therapeutic effect of Qingyi decoction in severe acute pancreatitis-induced intestinal barrier injury

, 2015
Jingwen Zhang
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Correction: Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategies. [PDF]

Cell Death Dis
Chen Y, Liu X, Liu Y, Li Y, Li D, Mei Z, Deng Y.   +6 more
europepmc   +1 more source