Results 211 to 220 of about 19,750,469 (329)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

MitoQ alleviates mitochondria damage in sepsis-acute lung injury in a citrate synthase dependent manner. [PDF]

Inflamm Res
Sun J, Jin S, Wang Z.
europepmc   +1 more source

Spallation-Fission Competition in Heaviest Elements; Helium-Ion-Induced Reactions in Uranium Isotopes [PDF]

, 1958
R. Vandenbosch, T. Darrah Thomas, S.E. Vandenbosch, R.A. Glass, Glenn T. Seaborg   +4 more
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Luteolin Potentially Alleviates Methamphetamine Withdrawal-Induced Negative Emotions and Cognitive Deficits Through the AKT/FOXO1/HO-1 Signaling Pathway in the Prefrontal Cortex and Caudate Putamen. [PDF]

Int J Mol Sci
Gao B, An R, Liang M, Wang X, Peng J, Chen X, Liu Z, Li T, Liu X, Zhang J, Han W.   +10 more
europepmc   +1 more source

What conditions induce conjugation in Paramecium? [PDF]

, 1910
H. S. Jennings
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Propuesta de enfoque diagnóstico y terapéutico de la carcinomatosis peritoneal originada en el colon

Revista Colombiana de Cirugía
Introducción. El cáncer colorrectal corresponde a la cuarta causa de cáncer a nivel mundial, con una incidencia de 17,2 por cada 100.000 habitantes, y en Colombia es de 10,6 por 100.000, con gran mortalidad. El cáncer metastásico a peritoneo se considera
Mauricio García, Jesús Esquivel, Angélica María Gutiérrez   +2 more
doaj  

Lesion-Induced Blepharospasm: Epidemiology and Clinical Characteristics. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Myller E, Halonen R, Corp DT, Joutsa J.
europepmc   +1 more source

A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics

Cell, 2007
Michael A. Kohanski, D. Dwyer, B. Hayete, Carolyn A. Lawrence, J. Collins   +4 more
semanticscholar   +1 more source