Results 31 to 40 of about 76,226 (325)

Addition of melatonin to hypothermia therapy for neonatal hypoxic-ischemic encephalopathy

Medwave, 2022
Introduction Neonatal hypoxic-ischemic encephalopathy is caused by perinatal asphyxia, resulting in an acute neurological dysfunction of variable severity.
Victor Meza V., Paulina Toso M.
doaj   +1 more source

Hypothermia Reduces Mortality, Prevents the Calcium Plateau, and Is Neuroprotective Following Status Epilepticus in Rats

Frontiers in Neurology, 2018
Status Epilepticus (SE) is a major neurological emergency and is considered a leading cause of Acquired Epilepsy (AE). We have shown that SE produces neuronal injury and prolonged alterations in hippocampal calcium levels ([Ca2+]i) that may underlie the ...
Kristin F. Phillips, Laxmikant S. Deshpande, Laxmikant S. Deshpande, Robert J. DeLorenzo, Robert J. DeLorenzo   +4 more
doaj   +1 more source

Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery

Frontiers in Molecular Neuroscience, 2020
Background: Hypothermia attenuates microglial activation and exerts a potential neuroprotective effect against cerebral ischemic-reperfusion (I/R) injury. However, the underlying mechanism remains to be elucidated.
Shen Zhao, Shen Zhao, Peng Xiao, Peng Xiao, Hao Cui, Hao Cui, Ping Gong, Caijing Lin, Caijing Lin, Feng Chen, Feng Chen, Ziren Tang, Ziren Tang   +12 more
doaj   +1 more source

The effect of hypothermia therapy on cortical laminar disruption following ischemic injury in neonatal mice. [PDF]

PLoS ONE, 2013
Hypothermia has been proposed as a treatment for reducing neuronal damage in the brain induced by hypoxic ischemia. In the developing brain, hypoxic ischemia-induced injury may give rise to cerebral palsy (CP).
Hiroyuki Kida, Sadahiro Nomura, Mizuya Shinoyama, Makoto Ideguchi, Yuji Owada, Michiyasu Suzuki   +5 more
doaj   +1 more source

Brain Death and Its Prediction in Out-of-Hospital Cardiac Arrest Patients Treated with Targeted Temperature Management

Diagnostics, 2022
Evolution toward brain death (BD) in out-of-hospital cardiac arrest patients with targeted temperature management (TTM) provides opportunities for organ donation. However, knowledge regarding BD in these patients is limited.
Hwan Song, Sang Hoon Oh, Hye Rim Woo, on behalf of CROWN Investigators   +3 more
doaj   +1 more source

Therapeutic hypothermia reduces inflammation and oxidative stress in the liver after asphyxial cardiac arrest in rats [PDF]

Acute and Critical Care, 2020
Background Few studies have evaluated the effects of hypothermia on cardiac arrest (CA)-induced liver damage. This study aimed to investigate the effects of hypothermic therapy on the liver in a rat model of asphyxial cardiac arrest (ACA).
Yoonsoo Park, Ji Hyeon Ahn, Tae-Kyeong Lee, Bora Kim, Hyun-Jin Tae, Joon Ha Park, Myoung Cheol Shin, Jun Hwi Cho, Moo-Ho Won   +8 more
doaj   +1 more source

Pharmacodynamic properties for inhibition of cAMP- and cGMP elimination by pentoxifylline remain unaltered in vitro during hypothermia

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2022
Background Rewarming from hypothermia is associated with severe complications, one of which is hypothermia-induced cardiac dysfunction. This condition is characterized by decreased cardiac output accompanied by increased total peripheral resistance. This
Anders Lund Selli, Adrina Kalasho Kuzmiszyn, Natalia Smaglyukova, Timofey Kondratiev, Ole-Martin Fuskevåg, Georg Sager, Erik Sveberg Dietrichs   +6 more
doaj   +1 more source

Scalp cooling with adjuvant/neoadjuvant chemotherapy for breast cancer and the risk of scalp metastases: systematic review and meta-analysis. [PDF]

, 2017
PurposeThe risk of scalp metastases in patients using scalp cooling for preservation of hair during chemotherapy has been a concern but is poorly described.MethodsA systematic review and meta-analysis of longitudinal studies was undertaken to evaluate ...
Melin, Susan A, Rugo, Hope S, Voigt, Jeff   +2 more
core   +1 more source

Effects of therapeutic hypothermia on white matter injury from murine neonatal hypoxia-ischemia. [PDF]

, 2017
BackgroundTherapeutic hypothermia (TH) is the standard of care for neonates with hypoxic-ischemic encephalopathy, but it is not fully protective in the clinical setting.
Ferriero, Donna M, Koo, Elliot, Lee, Byong Sop, Sheldon, R Ann, Vexler, Zinaida S   +4 more
core   +2 more sources

Neuroprotection by Therapeutic Hypothermia

Frontiers in Neuroscience, 2019
Hypothermia therapy is an old and important method of neuroprotection. Until now, many neurological diseases such as stroke, traumatic brain injury, intracranial pressure elevation, subarachnoid hemorrhage, spinal cord injury, hepatic encephalopathy, and
Ying-Jian Sun, Zi-Yuan Zhang, Bin Fan, Guang-Yu Li   +3 more
doaj   +1 more source