Results 61 to 70 of about 80,002 (339)

Effect of hypothermia on haemostasis and bleeding risk: a narrative review

Journal of International Medical Research, 2019
It must be remembered that clinically important haemostasis occurs in vivo and not in a tube, and that variables such as the number of bleeding events and bleeding volume are more robust measures of bleeding risk than the results of analyses.
Thomas Kander, Ulf Schött
doaj   +1 more source

Cold Shock Induced Protein RBM3 but Not Mild Hypothermia Protects Human SH-SY5Y Neuroblastoma Cells From MPP+-Induced Neurotoxicity

Frontiers in Neuroscience, 2018
The cold shock protein RBM3 can mediate mild hypothermia-related protection in neurodegeneration such as Alzheimer's disease. However, it remains unclear whether RBM3 and mild hypothermia provide same protection in model of Parkinson's disease (PD), the ...
Hai-Jie Yang, Hai-Jie Yang, Xiang Shi, Fei Ju, Bei-Ning Hao, Shuang-Ping Ma, Lei Wang, Bin-Feng Cheng, Mian Wang   +8 more
doaj   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Hypothermia protects the brain from transient global ischemia/reperfusion by attenuating endoplasmic reticulum response-induced apoptosis through CHOP. [PDF]

PLoS ONE, 2013
Endoplasmic reticulum (ER) stress has been implicated in the pathology of cerebral ischemia. Apoptotic cell death occurs during prolonged period of stress or when the adaptive response fails.
Xiaojie Liu, Mingshan Wang, Huailong Chen, Yunliang Guo, Fuguo Ma, Fei Shi, Yanlin Bi, Ying Li   +7 more
doaj   +1 more source

Altering temperature in a mammalian body [PDF]

, 2013
The present application relates to systems and methods for altering temperature in a mammalian body. Optionally, the systems and methods can be used to lower or raise core body temperature of a mammalian subject.
Diller, Kenneth R., Diller, Timothy T., Hensley, Daniel W.   +2 more
core   +1 more source

POSS Polyimide Composite Sealed Triple‐Junction GaAs Thin‐Film Solar Cell for Long‐Term Low Earth Orbit Serve

Advanced Science, EarlyView.
Ultrathin oxide layer and ultraviolet absorbent are introduced into polyhedral oligomeric silsesquioxane (POSS) polyimide to improve the transmittance conservation and realize near zero mass loss against ultraviolet and atomic oxygen exposures. The POSS polyimide composite sealed triple‐junction GaAs thin‐film solar cell exhibits enhanced endurance of ...
Min Qian, Min Wu, Xiaoyang Xuan, Yang Gao   +3 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

The Levels of Circulating MicroRNAs at 6-Hour Cardiac Arrest Can Predict 6-Month Poor Neurological Outcome

Diagnostics, 2021
Early prognostication in cardiac arrest survivors is challenging for physicians. Unlike other prognostic modalities, biomarkers are easily accessible and provide an objective assessment method.
Sang Hoon Oh, Ho-Shik Kim, Kyu Nam Park, Sanghee Ji, Ji-Young Park, Seung Pill Choi, Jee Yong Lim, Han Joon Kim, on behalf of CROWN Investigators   +8 more
doaj   +1 more source

Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1 [PDF]

, 2015
TNF is a central actor during inflammation and a well-recognized drug target for inflammatory diseases. We found that the mouse strain SPRET/Ei, known for extreme and dominant resistance against TNF-induced shock, displays weak expression of TNF receptor
Dejager, Lien, Libert, Claude, Lodens, Sofie, Puimège, Leen, Staelens, Jan, Steeland, Sophie, Timmermans, Steven, Van Hauwermeiren, Filip, Van Ryckeghem, Sara, Vandenbroucke, Roosmarijn, Vandevyver, Sofie, Vandewalle, Jolien   +11 more
core   +1 more source

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source