Results 41 to 50 of about 411,297 (242)

Reconstruction of a post-traumatic tibial defect of 10 cm in a 6 month old induced membrane by non-vascularised fibula autograft – A case report

Trauma Case Reports, 2022
Reconstruction of post-traumatic large bone defect in tibia is a surgical challenge. Masquelet technique is a two stage procedure to achieve bone union.
Ashutosh H. Bhosale
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The masquelet technique for severe open fractures: current insights

Journal of Orthopaedic Surgery and Research
Open fractures of the lower extremity remain challenging to manage even in the most experienced surgical teams. These injuries when they present with bone loss pose even greater challenges with often unpredictable outcomes.
Vasileios P. Giannoudis, Nikolaos K. Kanakaris, Peter V. Giannoudis   +2 more
doaj   +1 more source

Induced membrane technique for large bone defects

Medicine, 2022
Abstract. Aims:. The aim of this study was to evaluate the efficacy of induced membrane technique (IMT), and to analyze the relationships between patient factors and surgical parameters as well as their impacts on achieving bone union and complication rates. Materials and methods:.
Shih-Heng Sun, MD, Wen-Wen Tsai, MD, Sz-Iuan Shiu, MD, Chih-Hui Chen, MD, PhD   +3 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Comparison of two plates and screw osteosynthesis configurations in a rat model of critical sized femoral defects to reduce implant related failures

Scientific Reports
This study aimed to compare the failure rates of two different sizes of plates and screws to stabilize critical-sized (7 mm) femoral defects in male Sprague‒Dawley rats (aged 10 weeks).
Marc Saab, Anne-Sophie Drucbert, Nicolas Blanchemain, Feng Chai   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Masquelet induced membrane technique for treatment of rat chronic osteomyelitis

Experimental and Therapeutic Medicine, 2018
The application value of Masquelet induced membrane technique for the treatment of rat chronic osteomyelitis was explored. A total of 180 male Sprague-Dawley (SD) rats were randomly divided into sham operation group (control group), chronic osteomyelitis model group (model group) and Masquelet induced membrane therapy + chronic osteomyelitis model ...
Cui, Tao, Li, Junpeng, Zhen, Ping, Gao, Qiuming, Fan, Xiaohai, Li, Chuangbing   +5 more
openaire   +3 more sources