Results 201 to 210 of about 10,022,913 (342)

Duplex sequencing identifies unique characteristics of ENU-induced mutations in male mouse germ cells†. [PDF]

Biol Reprod
LeBlanc DPM, Zhou G, Williams A, Meier MJ, Valentine CC, Salk JJ, Yauk CL, Marchetti F.   +7 more
europepmc   +1 more source

Induced Gene Mutation [PDF]

, 2020
openaire   +1 more source

Efficient Genome-Wide Detection and Cataloging of EMS-Induced Mutations Using Exome Capture and Next-Generation Sequencing[C][W][OPEN]

The Plant Cell, 2014
I. Henry, Ugrappa Nagalakshmi, Meric C Lieberman, Kathie J. Ngo, Ksenia V. Krasileva, Hans A. Vasquez-Gross, Alina Akhunova, E. Akhunov, J. Dubcovsky, T. Tai, L. Comai   +10 more
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus. [PDF]

J Virol
Chen Z, Eggerman TL, Bocharov AV, Baranova IN, Vishnyakova TG, Patterson AP.   +5 more
europepmc   +1 more source

Hi-TOM: a platform for high-throughput tracking of mutations induced by CRISPR/Cas systems

Science China Life Sciences, 2017
Qing Liu, Chun Wang, Xiaozhen Jiao, Huawei Zhang, Lili Song, Yanxin Li, Caixia Gao, Kejian Wang   +7 more
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Never-germinating Arabidopsis seeds with LbCas12a-induced mutations in 6 clade A type 2C protein phosphatase genes. [PDF]

Plant Physiol
Xin C, Lu Y, Gul SL, Sun W, Cao Z, Kong X, Fan K, Li S, Liu X, Wang XC, Chen QJ.   +10 more
europepmc   +1 more source

FOXO3a acts to suppress DNA double-strand break-induced mutations. [PDF]

Aging Cell, 2020
White RR, Maslov AY, Lee M, Wilner SE, Levy M, Vijg J.   +5 more
europepmc   +1 more source