Results 41 to 50 of about 6,425,638 (291)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Meshing performance investigations on oblique worm drive

Journal of Advanced Mechanical Design, Systems, and Manufacturing
This paper proposed an innovative approach to oblique worm drive by introducing a specific inclination angle. The investigation focused on the meshing performance of oblique ZA worm drive by varying the crossed axis angle. The meshing geometric models of
Zhenglin YANG, Yonghong CHEN, Jin GAO, Wenjun LUO, Bingkui CHEN   +4 more
doaj   +1 more source

A Mathematical and Numerically Integrable Modeling of 3D Object Grasping under Rolling Contacts between Smooth Surfaces

Modelling and Simulation in Engineering, 2011
A computable model of grasping and manipulation of a 3D rigid object with arbitrary smooth surfaces by multiple robot fingers with smooth fingertip surfaces is derived under rolling contact constraints between surfaces.
Suguru Arimoto, Morio Yoshida
doaj   +1 more source

Effects of Lewis Number on the Evolution of Curvature in Spherically Expanding Turbulent Premixed Flames

Fluids, 2019
The effects of Lewis number on the physical mechanisms pertinent to the curvature evolution have been investigated using three-dimensional Direct Numerical Simulation (DNS) of spherically expanding turbulent premixed flames with characteristic Lewis ...
Ahmad Alqallaf, Markus Klein, Nilanjan Chakraborty   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Lunar and mars gravity induce similar changes in spinal motor control as microgravity

Frontiers in Physiology, 2023
Introduction: Once more, plans are underway to send humans to the Moon or possibly even to Mars. It is therefore, important to know potential physiological effects of a prolonged stay in space and to minimize possible health risks to astronauts.
Jaap Swanenburg, Jaap Swanenburg, Jaap Swanenburg, Christopher A. Easthope, Christopher A. Easthope, Anita Meinke, Anke Langenfeld, David A. Green, David A. Green, David A. Green, Petra Schweinhardt   +10 more
doaj   +1 more source

Curvature-induced enhancement of thermal stability of skyrmions

Journal of Applied Physics
Geometry plays an important role in the nucleation, stabilization, and manipulation of magnetization patterns within magnetic nanoelements. This work analyzes the impact of curvature on the thermal stability of skyrmions hosted on Gaussian-shaped ...
A. G. Silva-Junior, J. M. Fonseca, J. Costilla, M. M. Amaral, A. Riveros, V. L. Carvalho-Santos   +5 more
semanticscholar   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Constraints on primordial curvature power spectrum with kination era: Insights from NANOGrav 15-year data set

Nuclear Physics B
The stochastic signal detected by the NANOGrav, PPTA, EPTA, and CPTA collaborations can be attributed to gravitational waves induced by the primordial curvature perturbations generated during inflation.
Qin Fei, Fengfu Shen
doaj   +1 more source

Controlling Electronic Coherences and the Curvature Induced by the Derivative Coupling at a Conical Intersection: A Quantum Ehrenfest (QuEh) Protocol for Reaction Path Following Application to “Channel 3” Benzene Photochemistry

Journal of Physical Chemistry A
We report a protocol for the implementation of “reaction path following” from a transition state through a conical intersection, including both the path curvature induced by the derivative coupling and the corresponding induced electronic coherences ...
G. Worth, Michael A. Robb
semanticscholar   +1 more source