Results 181 to 190 of about 732,173 (296)

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Harnessing microbial consortia for induced systemic resistance and sustainable management of dry root rot in cluster bean under hot arid climatic conditions. [PDF]

Front Microbiol
Singh D, Verma A, Jadon KS, Mahla HR, Kakani RK.   +4 more
europepmc   +1 more source

Induced Systemic Resistance by a Plant Growth-Promoting Rhizobacterium Impacts Development and Feeding Behavior of Aphids. [PDF]

Insects, 2020
Serteyn L, Quaghebeur C, Ongena M, Cabrera N, Barrera A, Molina-Montenegro MA, Francis F, Ramírez CC.   +7 more
europepmc   +1 more source

Sprayable Polymer Blends With Short‐Chain Surface Segregation for Preventing Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III, Tejaswi Nori, Alex I. Halpern, Hannah LaPadula, Arthur V. Cresce, Sarah L. Wright, Anthony D. Sandler, Peter Kofinas   +7 more
wiley   +1 more source

Plant growth-promoting rhizobacteria enhanced induced systemic resistance of tomato against <i>Botrytis cinerea</i> phytopathogen. [PDF]

Front Plant Sci
Mazuecos-Aguilera I, Anta-Fernández F, Crespo-Barreiro A, Martínez-Quesada A, Lombana-Larrea L, González-Andrés F.   +5 more
europepmc   +1 more source

Investigating the Induced Systemic Resistance Mechanism of 2,4-Diacetylphloroglucinol (DAPG) using DAPG Hydrolase-Transgenic Arabidopsis. [PDF]

Plant Pathol J, 2020
Chae DH, Kim DR, Cheong MS, Lee YB, Kwak YS.   +4 more
europepmc   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Colonization by orchid mycorrhizal fungi primes induced systemic resistance against necrotrophic pathogen. [PDF]

Front Plant Sci
Pujasatria GC, Miura C, Yamaguchi K, Shigenobu S, Kaminaka H.   +4 more
europepmc   +1 more source

Isolation and identification of induced systemic resistance determinants from Bacillus simplex Sneb545 against Heterodera glycines. [PDF]

Sci Rep, 2020
Xing Z, Wu X, Zhao J, Zhao X, Zhu X, Wang Y, Fan H, Chen L, Liu X, Duan Y.   +9 more
europepmc   +1 more source